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Appears in Collections:Psychology Journal Articles
Peer Review Status: Refereed
Title: Adherence to angiotensin-converting-enzyme inhibitors and illness beliefs in older heart failure patients
Author(s): Molloy, Gerard
Gao, Chuan
Johnston, Derek W
Johnston, Marie
Witham, Miles D
Struthers, Allan D
McMurdo, Marion E T
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Keywords: Adherence
Illness perceptions
Heart failure
Issue Date: Jul-2009
Citation: Molloy G, Gao C, Johnston DW, Johnston M, Witham MD, Struthers AD & McMurdo MET (2009) Adherence to angiotensin-converting-enzyme inhibitors and illness beliefs in older heart failure patients, European Journal of Heart Failure, 11 (7), pp. 715-720.
Abstract: Objective: Patient beliefs about heart failure may be important determinants of adherence. This study assessed levels of adherence to angiotensin-converting enzyme inhibitors (ACEI) and examined whether beliefs about heart failure were associated with adherence to ACEI. Method: Fifty-eight patients with chronic stable heart failure (80.22 years SD: +4.62, 43% female) were recruited from outpatient clinics in Dundee Scotland. The Illness Perception Questionnaire-Revised (IPQ-R) was used to assess beliefs about heart failure. Adherence to ACEI was assessed by measuring serum levels of angiotensin-converting enzyme (sACE). Results: Adherence to ACEI (defined as sACE < 5 µ/l) was 72%. Beliefs about the time-line of heart failure and the consequences of heart failure accounted for 19% of the variability in adherence to ACE inhibitors in this sample. HF patients who believed that their illness had a more chronic (longer term) time frame and had beliefs about greater consequences of heart failure on their lives were less likely to adhere to ACEI. Conclusion: Adherence to ACEI is sub-optimal. Beliefs about heart failure appear to be associated with objectively measured adherence to ACEI. Future studies should attempt to identify beliefs that consistently predict adherence and examine whether modifying these beliefs can increase adherence to heart failure medications.
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Rights: Published in European Journal of Heart Failure by Oxford University Press.; This is a pre-copy-editing, author-produced PDF of an article accepted for publication in European Journal of Heart Failure following peer review. The definitive publisher-authenticated version European Journal of Heart Failure, Volume 11, Issue 7, July 2009, pp. 715 - 720 is available online at:

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