Please use this identifier to cite or link to this item:
Appears in Collections:Psychology Journal Articles
Peer Review Status: Refereed
Title: Urban-rural variations in quality-of-life in breast cancer survivors prescribed endocrine therapy
Author(s): Cahir, Catriona
Thomas, Audrey Alforque
Dombrowski, Stephan U
Bennett, Kathleen E
Sharp, Linda
Keywords: urban
quality of life
breast cancer
endocrine therapy
Issue Date: 7-Apr-2017
Citation: Cahir C, Thomas AA, Dombrowski SU, Bennett KE & Sharp L (2017) Urban-rural variations in quality-of-life in breast cancer survivors prescribed endocrine therapy, International Journal of Environmental Research and Public Health, 14 (4), Art. No.: 394.
Abstract: The number of breast cancer survivors has increased as a result of rising incidence and increased survival. Research has revealed significant urban–rural variation in clinical aspects of breast cancer but evidence in the area of survivorship is limited. We aimed to investigate whether quality of life (QoL) and treatment-related symptoms vary between urban and rural breast cancer survivors prescribed endocrine therapy. Women with a diagnosis of stages I–III breast cancer prescribed endocrine therapy were identified from the National Cancer Registry Ireland and invited to complete a postal survey (N= 1606; response rate = 66%). A composite measure of urban–rural classification was created using settlement size, population density and proximity to treatment hospital. QoL was measured using the Functional Assessment of Cancer Therapy (FACT-G) and an endocrine subscale. The association between urban–rural residence/status and QoL and endocrine symptoms was assessed using linear regression with adjustment for socio-demographic and clinical covariates. In multivariable analysis, rural survivors had a statistically significant higher overall QoL (β = 3.81, standard error (SE) 1.30,p< 0.01), emotional QoL (β = 0.70, SE 0.21,p< 0.01) and experienced a lower symptom burden (β = 1.76, SE 0.65,p< 0.01) than urban survivors. QoL in breast cancer survivors is not simply about proximity and access to healthcare services but may include individual and community level psychosocial factors.
DOI Link:
Rights: © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (

Files in This Item:
File Description SizeFormat 
ijerph-14-00394.pdf310.93 kBAdobe PDFView/Open

This item is protected by original copyright

Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.

If you believe that any material held in STORRE infringes copyright, please contact providing details and we will remove the Work from public display in STORRE and investigate your claim.