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dc.contributor.authorCahir, Catrionaen_UK
dc.contributor.authorThomas, Audrey Alforqueen_UK
dc.contributor.authorDombrowski, Stephan Uen_UK
dc.contributor.authorBennett, Kathleen Een_UK
dc.contributor.authorSharp, Lindaen_UK
dc.description.abstractThe number of breast cancer survivors has increased as a result of rising incidence and increased survival. Research has revealed significant urban–rural variation in clinical aspects of breast cancer but evidence in the area of survivorship is limited. We aimed to investigate whether quality of life (QoL) and treatment-related symptoms vary between urban and rural breast cancer survivors prescribed endocrine therapy. Women with a diagnosis of stages I–III breast cancer prescribed endocrine therapy were identified from the National Cancer Registry Ireland and invited to complete a postal survey (N= 1606; response rate = 66%). A composite measure of urban–rural classification was created using settlement size, population density and proximity to treatment hospital. QoL was measured using the Functional Assessment of Cancer Therapy (FACT-G) and an endocrine subscale. The association between urban–rural residence/status and QoL and endocrine symptoms was assessed using linear regression with adjustment for socio-demographic and clinical covariates. In multivariable analysis, rural survivors had a statistically significant higher overall QoL (β = 3.81, standard error (SE) 1.30,p< 0.01), emotional QoL (β = 0.70, SE 0.21,p< 0.01) and experienced a lower symptom burden (β = 1.76, SE 0.65,p< 0.01) than urban survivors. QoL in breast cancer survivors is not simply about proximity and access to healthcare services but may include individual and community level psychosocial factors.en_UK
dc.relationCahir C, Thomas AA, Dombrowski SU, Bennett KE & Sharp L (2017) Urban-rural variations in quality-of-life in breast cancer survivors prescribed endocrine therapy. International Journal of Environmental Research and Public Health, 14 (4), Art. No.: 394.
dc.rights© 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (
dc.subjectquality of lifeen_UK
dc.subjectbreast canceren_UK
dc.subjectendocrine therapyen_UK
dc.titleUrban-rural variations in quality-of-life in breast cancer survivors prescribed endocrine therapyen_UK
dc.typeJournal Articleen_UK
dc.citation.jtitleInternational Journal of Environmental Research and Public Healthen_UK
dc.type.statusVoR - Version of Recorden_UK
dc.contributor.affiliationRoyal College of Surgeons (Ireland)en_UK
dc.contributor.affiliationUniversity of California, Berkeleyen_UK
dc.contributor.affiliationRoyal College of Surgeons (Ireland)en_UK
dc.contributor.affiliationNewcastle Universityen_UK
Appears in Collections:Psychology Journal Articles

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