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Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/19305
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dc.contributor.authorCoates, Christopheren_UK
dc.contributor.authorNairn, Jacquelineen_UK
dc.date.accessioned2014-06-06T23:43:25Z-
dc.date.available2014-06-06T23:43:25Z-
dc.date.issued2014-07en_UK
dc.identifier.urihttp://hdl.handle.net/1893/19305-
dc.description.abstractSubstantial evidence gathered recently has revealed the multiple functionalities of hemocyanin. Contrary to previous claims that this ancient protein is involved solely in oxygen transport within the hemolymph of invertebrates, hemocyanin and hemocyanin-derived peptides have been linked to key aspects of innate immunity, in particular, antiviral and phenoloxidase-like activities. Both phenoloxidase and hemocyanin belong to the family of type-3 copper proteins and share a high degree of sequence homology. While the importance of phenoloxidase in immunity and development is well characterised, the contribution of hemocyanin to biological defence systems within invertebrates is not recognised widely. This review focusses on the conversion of hemocyanin into a phenoloxidase-like enzyme and the array of hemocyanin-derived immune responses documented to date.en_UK
dc.language.isoenen_UK
dc.publisherElsevieren_UK
dc.relationCoates C & Nairn J (2014) Diverse Immune Functions of Hemocyanins. Developmental and Comparative Immunology, 45 (1), pp. 43-55. https://doi.org/10.1016/j.dci.2014.01.021en_UK
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.en_UK
dc.rights.urihttp://www.rioxx.net/licenses/under-embargo-all-rights-reserveden_UK
dc.subjectMultifunctionalen_UK
dc.subjectHemocyaninen_UK
dc.subjectPhenoloxidaseen_UK
dc.subjectMicrobicidalen_UK
dc.subjectInnate immunityen_UK
dc.subjectHemoglobinen_UK
dc.titleDiverse Immune Functions of Hemocyaninsen_UK
dc.typeJournal Articleen_UK
dc.rights.embargodate3000-01-01en_UK
dc.rights.embargoreason[8_Coates and Nairn 2014 Devel Comp Immunol.pdf] The publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.en_UK
dc.identifier.doi10.1016/j.dci.2014.01.021en_UK
dc.citation.jtitleDevelopmental and Comparative Immunologyen_UK
dc.citation.issn0145-305Xen_UK
dc.citation.volume45en_UK
dc.citation.issue1en_UK
dc.citation.spage43en_UK
dc.citation.epage55en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedRefereeden_UK
dc.type.statusVoR - Version of Recorden_UK
dc.author.emailc.j.coates@stir.ac.uken_UK
dc.citation.date31/01/2014en_UK
dc.contributor.affiliationBiological and Environmental Sciencesen_UK
dc.contributor.affiliationBiological and Environmental Sciencesen_UK
dc.identifier.isiWOS:000335624800005en_UK
dc.identifier.scopusid2-s2.0-84896695417en_UK
dc.identifier.wtid657429en_UK
dc.date.accepted2014-01-25en_UK
dcterms.dateAccepted2014-01-25en_UK
dc.date.filedepositdate2014-02-26en_UK
rioxxterms.apcnot requireden_UK
rioxxterms.typeJournal Article/Reviewen_UK
rioxxterms.versionVoRen_UK
local.rioxx.authorCoates, Christopher|en_UK
local.rioxx.authorNairn, Jacqueline|en_UK
local.rioxx.projectInternal Project|University of Stirling|https://isni.org/isni/0000000122484331en_UK
local.rioxx.freetoreaddate3000-01-01en_UK
local.rioxx.licencehttp://www.rioxx.net/licenses/under-embargo-all-rights-reserved||en_UK
local.rioxx.filename8_Coates and Nairn 2014 Devel Comp Immunol.pdfen_UK
local.rioxx.filecount1en_UK
local.rioxx.source0145-305Xen_UK
Appears in Collections:Biological and Environmental Sciences Journal Articles

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