Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/9113
Full metadata record
DC FieldValueLanguage
dc.contributor.authorMathews, Fionaen_UK
dc.contributor.authorMacdonald, Daviden_UK
dc.contributor.authorTaylor, G Michaelen_UK
dc.contributor.authorGelling, Merrylen_UK
dc.contributor.authorNorman, Rachelen_UK
dc.contributor.authorHoness, Paulen_UK
dc.contributor.authorFoster, Rebeccaen_UK
dc.contributor.authorGower, Charlotte Men_UK
dc.contributor.authorVarley, Susanen_UK
dc.contributor.authorHarris, Audreyen_UK
dc.contributor.authorPalmer, Simonetteen_UK
dc.contributor.authorHewinson, Glynen_UK
dc.contributor.authorWebster, Joanne Pen_UK
dc.date.accessioned2012-09-17T10:35:09Z-
dc.date.available2012-09-17T10:35:09Zen_UK
dc.date.issued2006-02-07en_UK
dc.identifier.urihttp://hdl.handle.net/1893/9113-
dc.description.abstractBovine tuberculosis (bTB) is an important disease of cattle and an emerging infectious disease of humans. Cow- and badger-based control strategies have failed to eradicate bTB from the British cattle herd, and the incidence is rising by about 18% per year. The annual cost to taxpayers in Britain is currently £74 million. Research has focused on the badger as a potential bTB reservoir, with little attention being paid to other mammals common on farmland. We have conducted a systematic survey of wild mammals (n=4393 individuals) present on dairy farms to explore the role of species other than badgers in the epidemiology of bTB. Cultures were prepared from 10 397 samples (primarily faeces, urine and tracheal aspirates). One of the 1307 bank voles (Clethrionomys glareolus) live-sampled, and three of the 43 badgers (Meles meles), yielded positive isolates of Mycobacterium bovis. This is the first time the bacterium has been isolated from the bank vole. The strain type was the same as that found in cattle and badgers on the same farm. However, our work indicates that the mean prevalence of infectious individuals among common farmland wildlife is extremely low (the upper 95% confidence interval is ≤2.0 for all of the abundant species). Mathematical models illustrate that it is highly unlikely the disease could be maintained at such low levels. Our results suggest that these animals are relatively unimportant as reservoirs of bTB, having insufficient withinspecies (or within-group) transmission to sustain the infection, though occasional spill-overs from cattle or badgers may occur.en_UK
dc.language.isoenen_UK
dc.publisherThe Royal Societyen_UK
dc.relationMathews F, Macdonald D, Taylor GM, Gelling M, Norman R, Honess P, Foster R, Gower CM, Varley S, Harris A, Palmer S, Hewinson G & Webster JP (2006) Bovine tuberculosis (Mycobacterium bovis) in British farmland wildlife: the importance to agriculture. Proceedings of the Royal Society B: Biological Sciences, 273 (1584), pp. 357-365. http://rspb.royalsocietypublishing.org/content/273/1584/357; https://doi.org/10.1098/rspb.2005.3298en_UK
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.en_UK
dc.subjectbovine tuberculosisen_UK
dc.subjectMycobacterium bovisen_UK
dc.subjectepidemiologyen_UK
dc.subjectvolesen_UK
dc.subjectPCRen_UK
dc.subjectmycobacterium microtien_UK
dc.titleBovine tuberculosis (Mycobacterium bovis) in British farmland wildlife: the importance to agricultureen_UK
dc.typeJournal Articleen_UK
dc.rights.embargodate2999-12-08en_UK
dc.rights.embargoreason[357.full.pdf] The publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.en_UK
dc.identifier.doi10.1098/rspb.2005.3298en_UK
dc.citation.jtitleProceedings of the Royal Society B: Biological Sciencesen_UK
dc.citation.issn1471-2954en_UK
dc.citation.issn0962-8452en_UK
dc.citation.volume273en_UK
dc.citation.issue1584en_UK
dc.citation.spage357en_UK
dc.citation.epage365en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedRefereeden_UK
dc.type.statusVoR - Version of Recorden_UK
dc.identifier.urlhttp://rspb.royalsocietypublishing.org/content/273/1584/357en_UK
dc.author.emailran@maths.stir.ac.uken_UK
dc.contributor.affiliationUniversity of Oxforden_UK
dc.contributor.affiliationUniversity of Oxforden_UK
dc.contributor.affiliationImperial College Londonen_UK
dc.contributor.affiliationUniversity of Oxforden_UK
dc.contributor.affiliationMathematicsen_UK
dc.contributor.affiliationUniversity of Oxforden_UK
dc.contributor.affiliationUniversity of Oxforden_UK
dc.contributor.affiliationUniversity of Oxforden_UK
dc.contributor.affiliationUniversity of Oxforden_UK
dc.contributor.affiliationDepartment for Environment Food & Rural Affairs (DEFRA)en_UK
dc.contributor.affiliationVeterinary Laboratories Agencyen_UK
dc.contributor.affiliationVeterinary Laboratories Agencyen_UK
dc.contributor.affiliationUniversity of Oxforden_UK
dc.identifier.isiWOS:000234978100013en_UK
dc.identifier.scopusid2-s2.0-34248680780en_UK
dc.identifier.wtid775720en_UK
dc.contributor.orcid0000-0002-7398-6064en_UK
dc.date.filedepositdate2012-09-14en_UK
Appears in Collections:Computing Science and Mathematics Journal Articles

Files in This Item:
File Description SizeFormat 
357.full.pdfFulltext - Published Version247.12 kBAdobe PDFUnder Embargo until 2999-12-08    Request a copy


This item is protected by original copyright



Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.

If you believe that any material held in STORRE infringes copyright, please contact library@stir.ac.uk providing details and we will remove the Work from public display in STORRE and investigate your claim.