Please use this identifier to cite or link to this item:
Appears in Collections:Psychology Journal Articles
Peer Review Status: Refereed
Title: Hippocampal place cells encode intended destination, and not a discriminative stimulus, in a conditional T-maze task
Author(s): Ainge, James A
Tamosiunaite, Minija
Worgotter, Florentin
Dudchenko, Paul
Contact Email:
Keywords: Spatial cognition
Trajectory encoding
Place fields
Hippocampus (Brain)
Issue Date: Mar-2012
Date Deposited: 10-Sep-2012
Citation: Ainge JA, Tamosiunaite M, Worgotter F & Dudchenko P (2012) Hippocampal place cells encode intended destination, and not a discriminative stimulus, in a conditional T-maze task. Hippocampus, 22 (3), pp. 534-543.
Abstract: The firing of hippocampal place cells encodes instantaneous location but can also reflect where the animal is heading (prospective firing), or where it has just come from (retrospective firing). The current experiment sought to explicitly control the prospective firing of place cells with a visual discriminada in a T-maze. Rats were trained to associate a specific visual stimulus (e.g., a flashing light) with the occurrence of reward in a specific location (e.g., the left arm of the T). A different visual stimulus (e.g., a constant light) signaled the availability of reward in the opposite arm of the T. After this discrimination had been acquired, rats were implanted with electrodes in the CA1 layer of the hippocampus. Place cells were then identified and recorded as the animals performed the discrimination task, and the presentation of the visual stimulus was manipulated. A subset of CA1 place cells fired at different rates on the central stem of the T depending on the animal's intended destination, but this conditional or prospective firing was independent of the visual discriminative stimulus. The firing rate of some place cells was, however, modulated by changes in the timing of presentation of the visual stimulus. Thus, place cells fired prospectively, but this firing did not appear to be controlled, directly, by a salient visual stimulus that controlled behavior.
DOI Link: 10.1002/hipo.20919
Rights: The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.
Licence URL(s):

Files in This Item:
File Description SizeFormat 
Dudchenko_2012_Hippocampal_Place_Cells.pdfFulltext - Published Version1.22 MBAdobe PDFUnder Embargo until 3000-01-01    Request a copy

Note: If any of the files in this item are currently embargoed, you can request a copy directly from the author by clicking the padlock icon above. However, this facility is dependent on the depositor still being contactable at their original email address.

This item is protected by original copyright

Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.

The metadata of the records in the Repository are available under the CC0 public domain dedication: No Rights Reserved

If you believe that any material held in STORRE infringes copyright, please contact providing details and we will remove the Work from public display in STORRE and investigate your claim.