|Appears in Collections:||Faculty of Health Sciences and Sport Journal Articles|
|Peer Review Status:||Refereed|
|Title:||Adherence to insulin and its association with glycaemic control in patients with type 2 diabetes|
|Author(s):||Donnelly, Louise A|
Morris, Andrew D
Diabetes Mellitus, Type 2
|Citation:||Donnelly LA, Morris AD & Evans J (2007) Adherence to insulin and its association with glycaemic control in patients with type 2 diabetes. QJM, 100 (6), pp. 345-350. https://doi.org/10.1093/qjmed/hcm031|
|Abstract:||Background: Good glycaemic control improves outcomes in patients with type 2 diabetes, but the extent to which this depends on adherence to insulin treatment is uncertain. Aim: To investigate the association between adherence to insulin and glycaemic control in insulintreated patients with type 2 diabetes. Design: Observational records-based study. Methods: We studied all patients with type 2 diabetes who were resident in Tayside, Scotland from 1 January 1995 to 30 September 2001, and who were treated with insulin. Adherence to insulin treatment was measured as the annual number of days of insulin coverage on the recommended dose, calculated from the amount of drug dispensed at community pharmacies and the recommended dose level for each patient. The association between glycaemic control (HbA1c), and adherence was determined, as was the influence of covariates, including age, sex, duration of diabetes and number of injections per day. Results: A total of 1099 people were studied: 574 (52%) males and 525 (48%) females, meanSD age 6212 years, diabetes duration 107 years. Median time in the study (time for which insulin was dispensed) was 1107 (range 366-2446) days. Insulin prescribed was 58.033.3 IU/day and insulin collected from pharmacies was 53.627.1 IU/day. Mean adherence to insulin was thus 70.6%17.7%. Adherence to insulin (p=0.0021), BMI (p=0.0001) and diabetes duration (p=0.0314) were all significant predictors of HbA1c. Discussion: Adherence to insulin appears poor in these type 2 diabetes patients, and there was a significant relationship between adherence and long-term metabolic control.|
|Rights:||The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.|
|Evans_2007_Adherence_to_insulin.pdf||Fulltext - Published Version||90.19 kB||Adobe PDF||Under Embargo until 2999-12-16 Request a copy|
Note: If any of the files in this item are currently embargoed, you can request a copy directly from the author by clicking the padlock icon above. However, this facility is dependent on the depositor still being contactable at their original email address.
This item is protected by original copyright
Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.
The metadata of the records in the Repository are available under the CC0 public domain dedication: No Rights Reserved https://creativecommons.org/publicdomain/zero/1.0/
If you believe that any material held in STORRE infringes copyright, please contact firstname.lastname@example.org providing details and we will remove the Work from public display in STORRE and investigate your claim.