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dc.contributor.authorDonnelly, Louise Aen_UK
dc.contributor.authorMorris, Andrew Den_UK
dc.contributor.authorEvans, Josieen_UK
dc.description.abstractBackground: Good glycaemic control improves outcomes in patients with type 2 diabetes, but the extent to which this depends on adherence to insulin treatment is uncertain. Aim: To investigate the association between adherence to insulin and glycaemic control in insulintreated patients with type 2 diabetes. Design: Observational records-based study. Methods: We studied all patients with type 2 diabetes who were resident in Tayside, Scotland from 1 January 1995 to 30 September 2001, and who were treated with insulin. Adherence to insulin treatment was measured as the annual number of days of insulin coverage on the recommended dose, calculated from the amount of drug dispensed at community pharmacies and the recommended dose level for each patient. The association between glycaemic control (HbA1c), and adherence was determined, as was the influence of covariates, including age, sex, duration of diabetes and number of injections per day. Results: A total of 1099 people were studied: 574 (52%) males and 525 (48%) females, meanSD age 6212 years, diabetes duration 107 years. Median time in the study (time for which insulin was dispensed) was 1107 (range 366-2446) days. Insulin prescribed was 58.033.3 IU/day and insulin collected from pharmacies was 53.627.1 IU/day. Mean adherence to insulin was thus 70.6%17.7%. Adherence to insulin (p=0.0021), BMI (p=0.0001) and diabetes duration (p=0.0314) were all significant predictors of HbA1c. Discussion: Adherence to insulin appears poor in these type 2 diabetes patients, and there was a significant relationship between adherence and long-term metabolic control.en_UK
dc.publisherOxford University Press for the Association of Physicians of Great Britain and Irelanden_UK
dc.relationDonnelly LA, Morris AD & Evans J (2007) Adherence to insulin and its association with glycaemic control in patients with type 2 diabetes. QJM, 100 (6), pp. 345-350.
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.en_UK
dc.subjectNon-insulin-dependent diabetesen_UK
dc.subjectDiabetes Mellitus, Type 2en_UK
dc.titleAdherence to insulin and its association with glycaemic control in patients with type 2 diabetesen_UK
dc.typeJournal Articleen_UK
dc.rights.embargoreason[Evans_2007_Adherence_to_insulin.pdf] The publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.en_UK
dc.citation.jtitleQJM: An International Journal of Medicineen_UK
dc.type.statusVoR - Version of Recorden_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationHealth Sciences Research - Stirling - LEGACYen_UK
rioxxterms.typeJournal Article/Reviewen_UK
local.rioxx.authorDonnelly, Louise A|en_UK
local.rioxx.authorMorris, Andrew D|en_UK
local.rioxx.authorEvans, Josie|0000-0001-6672-7876en_UK
local.rioxx.projectInternal Project|University of Stirling|
Appears in Collections:Faculty of Health Sciences and Sport Journal Articles

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