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dc.contributor.authorWalshe, Crionaen_UK
dc.contributor.authorBourke, Janeen_UK
dc.contributor.authorLynch, Maureenen_UK
dc.contributor.authorMcGovern, Marken_UK
dc.contributor.authorDelaney, Liamen_UK
dc.contributor.authorPhelan, Dermoten_UK
dc.description.abstractA relationship between central venous catheter (CVC) tip colonisation and catheter-related blood-stream infection (CRBSI) has been suggested. We examined culture positivity of CVC tips (colonised and infected CVCs) in a total parenteral nutrition (TPN) population. Our aims were to define the relationship between culture positivity and CRBSI, and to compare causative organisms between culture positive and CRBSI CVCS, and between ward and ICU CVCs. All patients receiving TPN via non-tunnelled CVCs during the study (1997-2009) were included. All CVC tips were analysed. Data were collated contemporaneously. A TPN audit committee determined whether CVC tip culture positivity reflected colonisation/CRBSI using CDC criteria. 1,392 patients received TPN via 2,565 CVCs over 15,397 CVC days. 25.4% of CVCs tips were culture positive, of these 32% developed CRBSI. There was a nonsignificant trend of higher Gram negative Bacilli isolation in ICU CVCs ( P = 0 . 1 ) , ward CVCs were associated with higher rates of staphylococcal isolation ( P = 0 . 0 1 ) . A similar pattern of organisms were cultured from CRBSI and culture positive CVCs. The consistent relationship between CRBSI and culture positive CVCs, and similar pattern of causative organisms further supports an aetiological relationship between culture positive CVC tips and CRBSI, supporting the contention that CVC culture-positivity may be a useful surrogate marker for CRBSI rates.en_UK
dc.publisherHindawi Publishing Corporationen_UK
dc.relationWalshe C, Bourke J, Lynch M, McGovern M, Delaney L & Phelan D (2012) Culture Positivity of CVCs Used for TPN: Investigation of an Association with Catheter-Related Infection and Comparison of Causative Organisms between ICU and Non-ICU CVCs. Journal of Nutrition and Metabolism, 2012, p. Article 257959.
dc.rightsPublisher is open-access. Open Access authors retain the copyrights of their papers, and all open access articles are distributed under the terms of the Creative Commons Attribution license, which permits unrestricted use, distribution and reproduction in any medium, provided that the original work is properly cited.en_UK
dc.titleCulture Positivity of CVCs Used for TPN: Investigation of an Association with Catheter-Related Infection and Comparison of Causative Organisms between ICU and Non-ICU CVCsen_UK
dc.typeJournal Articleen_UK
dc.citation.jtitleJournal of Nutrition and Metabolismen_UK
dc.citation.spageArticle 257959en_UK
dc.type.statusVoR - Version of Recorden_UK
dc.contributor.affiliationMater Misericordiae University Hospitalen_UK
dc.contributor.affiliationMater Misericordiae University Hospitalen_UK
dc.contributor.affiliationMater Misericordiae University Hospitalen_UK
dc.contributor.affiliationUniversity College Dublin (UCD)en_UK
dc.contributor.affiliationMater Misericordiae University Hospitalen_UK
rioxxterms.typeJournal Article/Reviewen_UK
local.rioxx.authorWalshe, Criona|en_UK
local.rioxx.authorBourke, Jane|en_UK
local.rioxx.authorLynch, Maureen|en_UK
local.rioxx.authorMcGovern, Mark|en_UK
local.rioxx.authorDelaney, Liam|en_UK
local.rioxx.authorPhelan, Dermot|en_UK
local.rioxx.projectInternal Project|University of Stirling|
Appears in Collections:Economics Journal Articles

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