Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/7536
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dc.contributor.authorNorman, Rachelen_UK
dc.contributor.authorChan, Man-Suenen_UK
dc.contributor.authorSrividya, AdiNarayananen_UK
dc.contributor.authorPani, S Pen_UK
dc.contributor.authorRamaiah, Kapa Den_UK
dc.contributor.authorVanamail, Perumalen_UK
dc.contributor.authorMichael, Edwinen_UK
dc.contributor.authorDas, Pradeep Ken_UK
dc.contributor.authorBundy, Don A Pen_UK
dc.date.accessioned2012-08-23T09:12:04Z-
dc.date.available2012-08-23T09:12:04Z-
dc.date.issued2000-06en_UK
dc.identifier.urihttp://hdl.handle.net/1893/7536-
dc.description.abstractMathematical models of transmission dynamics of infectious diseases provide a useful tool for investigating the impact of community based control measures. Previously, we used a dynamic (constant force-of-infection) model for lymphatic filariasis to describe observed patterns of infection and disease in endemic communities. In this paper, we expand the model to examine the effects of control options against filariasis by incorporating the impact of age structure of the human community and by addressing explicitly the dynamics of parasite transmission from and to the vector population. This model is tested using data for Wuchereria bancrofti transmitted by Culex quinquefasciatus in Pondicherry, South India. The results show that chemotherapy has a larger short-term impact than vector control but that the effects of vector control can last beyond the treatment period. In addition we compare rates of recrudescence for drugs with different macrofilaricidal effects.en_UK
dc.language.isoenen_UK
dc.publisherCambridge University Pressen_UK
dc.relationNorman R, Chan M, Srividya A, Pani SP, Ramaiah KD, Vanamail P, Michael E, Das PK & Bundy DAP (2000) EPIFIL: The development of an age-structured model for describing the transmission dynamics and control of lymphatic filariasis. Epidemiology and Infection, 124 (3), pp. 529-541. http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=54243; https://doi.org/10.1017/S0950268899003702en_UK
dc.rightsPublisher policy allows this work to be made available in this repository. Published in Epidemiology and Infection by Cambridge University Press, copyright 2000. Epidemiology and Infection, Volume 124, Issue 03, June 2000, pp 529-541. The original publication is available at http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=54243en_UK
dc.titleEPIFIL: The development of an age-structured model for describing the transmission dynamics and control of lymphatic filariasisen_UK
dc.typeJournal Articleen_UK
dc.identifier.doi10.1017/S0950268899003702en_UK
dc.citation.jtitleEpidemiology and Infectionen_UK
dc.citation.issn1469-4409en_UK
dc.citation.issn0950-2688en_UK
dc.citation.volume124en_UK
dc.citation.issue3en_UK
dc.citation.spage529en_UK
dc.citation.epage541en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedRefereeden_UK
dc.type.statusVoR - Version of Recorden_UK
dc.identifier.urlhttp://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=54243en_UK
dc.author.emailran@maths.stir.ac.uken_UK
dc.citation.date08/09/2000en_UK
dc.contributor.affiliationMathematicsen_UK
dc.contributor.affiliationUniversity of Oxforden_UK
dc.contributor.affiliationVector Control Research Centreen_UK
dc.contributor.affiliationVector Control Research Centreen_UK
dc.contributor.affiliationVector Control Research Centreen_UK
dc.contributor.affiliationVector Control Research Centreen_UK
dc.contributor.affiliationUniversity of Oxforden_UK
dc.contributor.affiliationVector Control Research Centreen_UK
dc.contributor.affiliationUniversity of Oxforden_UK
dc.identifier.isiWOS:000089037700022en_UK
dc.identifier.scopusid2-s2.0-0033869488en_UK
dc.identifier.wtid775644en_UK
dc.contributor.orcid0000-0002-7398-6064en_UK
dc.date.filedepositdate2012-08-22en_UK
Appears in Collections:Computing Science and Mathematics Journal Articles

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