Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/7387
Appears in Collections:Aquaculture Journal Articles
Peer Review Status: Refereed
Title: A single residue change in Vibrio harveyi hemolysin results in the loss of phospholipase and hemolytic activities and pathogenicity for turbot (Scophthalmus maximus)
Author(s): Sun, Boguang
Zhang, Xiao-Hua
Tang, Xuexi
Wang, Shushan
Zhong, Yingbin
Chen, Jixiang
Austin, Brian
Contact Email: brian.austin@stir.ac.uk
Issue Date: Mar-2007
Date Deposited: 9-Aug-2012
Citation: Sun B, Zhang X, Tang X, Wang S, Zhong Y, Chen J & Austin B (2007) A single residue change in Vibrio harveyi hemolysin results in the loss of phospholipase and hemolytic activities and pathogenicity for turbot (Scophthalmus maximus). Journal of Bacteriology, 189 (6), pp. 2575-2579. https://doi.org/10.1128/JB.01650-06
Abstract: Vibrio harveyi hemolysin, an important virulence determinant in fish pathogenesis, was further characterized, and the enzyme was identified as a phospholipase B by gas chromatography. Site-directed mutagenesis revealed that a specific residue, Ser153, was critical for its enzymatic activity and for its virulence in fish.
DOI Link: 10.1128/JB.01650-06
Rights: Publisher allows this work to be made available in this repository. Published in Journal of Bacteriology by American Society for Microbiology with the following policy: Authors may post their articles in full on personal or employer websites. ASM grants the author the right to post his/her article (after publication by ASM) on the author’s personal or university-hosted website, but not on any corporate, government, or similar website, without ASM’s prior permission, provided that proper credit is given to the original ASM publication.

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