Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/7302
Full metadata record
DC FieldValueLanguage
dc.contributor.authorPieters, Nen_UK
dc.contributor.authorBrunt, Jasonen_UK
dc.contributor.authorAustin, Brianen_UK
dc.contributor.authorLyndon, Alastair Ren_UK
dc.date.accessioned2012-08-08T14:28:57Z-
dc.date.available2012-08-08T14:28:57Zen_UK
dc.date.issued2008-09en_UK
dc.identifier.urihttp://hdl.handle.net/1893/7302-
dc.description.abstractAims: The aim of this study was to assess the efficacy of in-feed probiotics as a preventive measure against skin infections caused by Aeromonas bestiarum and Ichthyophthirius multifiliis (Ich) in rainbow trout. Methods and Results: Fin rot was induced in fish by intradermal injection with 0·1 ml volumes containing 105 cells per ml A. bestiarum at the base of the dorsal fin. Ich infections resulted from immersion in Ich-contaminated water. Each probiotic was administered orally [108 cells per g feed for GC2 (Aeromonas sobria) and 1010 cells per g feed for BA211 (Brochothrix thermosphacta)] for 14 days. Results showed that, after challenge with A. bestiarum, probiotics GC2 and BA211 led to 76% and 88% survival, respectively, in contrast to 22% survival for controls. Fish fed with probiotic GC2 had 100% survival after challenge with Ich compared with 2% for probiotic BA211 and 0% for controls. Analysis of innate immune responses revealed that probiotic GC2 promoted higher phagocytic activity, whereas probiotic BA211 led to enhanced respiratory burst activity. Conclusion: Of the two probiotics examined, GC2 was more effective in protecting against both fin rot and Ich. Each probiotic appeared to stimulate different pathways within the innate immune system. Significance and Impact of the Study: This is the first demonstration that probiotics can protect fish against surface infections. Furthermore, this is the first time a probiotic has been shown to protect against a eucaryotic pathogen, namely I. multifiliis.en_UK
dc.language.isoenen_UK
dc.publisherWiley-Blackwellen_UK
dc.relationPieters N, Brunt J, Austin B & Lyndon AR (2008) Efficacy of in-feed probiotics against Aeromonas bestiarum and Ichthyophthirius multifiliis skin infections in rainbow trout (Oncorhynchus mykiss, Walbaum). Journal of Applied Microbiology, 105 (3), pp. 723-732. https://doi.org/10.1111/j.1365-2672.2008.03817.xen_UK
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.en_UK
dc.rights.urihttp://www.rioxx.net/licenses/under-embargo-all-rights-reserveden_UK
dc.subjectAeromonas bestiarumen_UK
dc.subjectfin roten_UK
dc.subjectfishen_UK
dc.subjectIchen_UK
dc.subjectIchthyophthirius multifiliisen_UK
dc.subjectinnate immunityen_UK
dc.subjectprobioticsen_UK
dc.subjectwhite spoten_UK
dc.titleEfficacy of in-feed probiotics against Aeromonas bestiarum and Ichthyophthirius multifiliis skin infections in rainbow trout (Oncorhynchus mykiss, Walbaum)en_UK
dc.typeJournal Articleen_UK
dc.rights.embargodate2999-12-31en_UK
dc.rights.embargoreason[austin_infeedprobiotics_2008.pdf] The publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.en_UK
dc.identifier.doi10.1111/j.1365-2672.2008.03817.xen_UK
dc.citation.jtitleJournal of Applied Microbiologyen_UK
dc.citation.issn1365-2672en_UK
dc.citation.issn1364-5072en_UK
dc.citation.volume105en_UK
dc.citation.issue3en_UK
dc.citation.spage723en_UK
dc.citation.epage732en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedRefereeden_UK
dc.type.statusVoR - Version of Recorden_UK
dc.author.emailbrian.austin@stir.ac.uken_UK
dc.contributor.affiliationHeriot-Watt Universityen_UK
dc.contributor.affiliationHeriot-Watt Universityen_UK
dc.contributor.affiliationHeriot-Watt Universityen_UK
dc.contributor.affiliationHeriot-Watt Universityen_UK
dc.identifier.isiWOS:000258595600012en_UK
dc.identifier.wtid785752en_UK
dcterms.dateAccepted2008-09-30en_UK
dc.date.filedepositdate2012-08-08en_UK
rioxxterms.typeJournal Article/Reviewen_UK
rioxxterms.versionVoRen_UK
local.rioxx.authorPieters, N|en_UK
local.rioxx.authorBrunt, Jason|en_UK
local.rioxx.authorAustin, Brian|en_UK
local.rioxx.authorLyndon, Alastair R|en_UK
local.rioxx.projectInternal Project|University of Stirling|https://isni.org/isni/0000000122484331en_UK
local.rioxx.freetoreaddate2999-12-31en_UK
local.rioxx.licencehttp://www.rioxx.net/licenses/under-embargo-all-rights-reserved||en_UK
local.rioxx.filenameaustin_infeedprobiotics_2008.pdfen_UK
local.rioxx.filecount1en_UK
local.rioxx.source1364-5072en_UK
Appears in Collections:Aquaculture Journal Articles

Files in This Item:
File Description SizeFormat 
austin_infeedprobiotics_2008.pdfFulltext - Published Version168.5 kBAdobe PDFUnder Permanent Embargo    Request a copy


This item is protected by original copyright



Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.

The metadata of the records in the Repository are available under the CC0 public domain dedication: No Rights Reserved https://creativecommons.org/publicdomain/zero/1.0/

If you believe that any material held in STORRE infringes copyright, please contact library@stir.ac.uk providing details and we will remove the Work from public display in STORRE and investigate your claim.