Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/7229
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dc.contributor.authorNya, Elijah Jacoben_UK
dc.contributor.authorAustin, Brianen_UK
dc.date.accessioned2013-06-09T03:34:18Z-
dc.date.available2013-06-09T03:34:18Zen_UK
dc.date.issued2010-02en_UK
dc.identifier.urihttp://hdl.handle.net/1893/7229-
dc.description.abstractAims: To determine the effect of lipopolysaccharide (LPS) for the prevention of infection by Aeromonas hydrophila in rainbow trout (Oncorhynchus mykiss Walbaum) fingerlings.Methods and Results: Rainbow trout fingerlings were fed with 0 mg (= controls), 1.875 mg, 3.75 mg, 7.5 mg and 15 mg of LPS per 100 g of commercial feed for 14 days before experimental challenge with A. hydrophila. The results revealed a reduction in mortalities to 5% in the two lowest doses and 15% in the group, which received 15 mg LPS per 100 g of feed, compared with 45% mortalities in the control. LPS exerted a powerful oxidative burst effect and was a potent mediator of phagocytic, lysozyme, bactericidal and antiprotease activities and total protein. However, whereas there were increases in specific growth rate (SGR), feed conversion ratio (FCR) and protein efficiency ratio (PER) in LPS-treated fish, the data were not significantly (P > 0.05) different.Conclusions: LPS was effective at preventing disease caused by A. hydrophila and in stimulating the innate immune response of rainbow trout.Significance and Impact of the Study: The results of this study highlight the role of LPS in fish disease control.en_UK
dc.language.isoenen_UK
dc.publisherBlackwell Scienceen_UK
dc.relationNya EJ & Austin B (2010) Use of bacterial lipopolysaccharide (LPS) as an immunostimulant for the control of Aeromonas hydrophila infections in rainbow trout Oncorhynchus mykiss (Walbaum). Journal of Applied Microbiology, 108 (2), pp. 686-694. https://doi.org/10.1111/j.1365-2672.2009.04464.xen_UK
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.en_UK
dc.rights.urihttp://www.rioxx.net/licenses/under-embargo-all-rights-reserveden_UK
dc.subject100en_UK
dc.subjectactivitiesen_UK
dc.subjectAeromonas hydrophilaen_UK
dc.subjectBACTERIALen_UK
dc.subjectchallengeen_UK
dc.subjectControlen_UK
dc.subjectdataen_UK
dc.subjectDiseaseen_UK
dc.subjectEFFICIENCYen_UK
dc.subjectFEEDen_UK
dc.subjectfeed conversionen_UK
dc.subjectfishen_UK
dc.subjectGrowthen_UK
dc.subjectHealthen_UK
dc.subjectimmuneen_UK
dc.subjectimmune responseen_UK
dc.subjectIMMUNE-RESPONSEen_UK
dc.subjectIMPACTen_UK
dc.subjectINFECTIONen_UK
dc.subjectINFECTIONSen_UK
dc.subjectlysozymeen_UK
dc.subjectmethoden_UK
dc.subjectmethodsen_UK
dc.subjectMORTALITIESen_UK
dc.subjectMORTALITYen_UK
dc.subjectMYKISSen_UK
dc.subjectOncorhynchus mykissen_UK
dc.subjectONCORHYNCHUS-MYKISSen_UK
dc.subjectPreventionen_UK
dc.subjectPROTEINen_UK
dc.subjectrainbow trouten_UK
dc.subjectRAINBOW-TROUTen_UK
dc.subjectRATIOen_UK
dc.subjectreductionen_UK
dc.subjectRoleen_UK
dc.subjectTROUTen_UK
dc.subjectWALBAUMen_UK
dc.subjectwelfareen_UK
dc.titleUse of bacterial lipopolysaccharide (LPS) as an immunostimulant for the control of Aeromonas hydrophila infections in rainbow trout Oncorhynchus mykiss (Walbaum)en_UK
dc.typeJournal Articleen_UK
dc.rights.embargodate2999-12-29en_UK
dc.rights.embargoreason[austin_lipopolysaccharide_2009.pdf] The publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.en_UK
dc.identifier.doi10.1111/j.1365-2672.2009.04464.xen_UK
dc.citation.jtitleJournal of Applied Microbiologyen_UK
dc.citation.issn1365-2672en_UK
dc.citation.issn1364-5072en_UK
dc.citation.volume108en_UK
dc.citation.issue2en_UK
dc.citation.spage686en_UK
dc.citation.epage694en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedRefereeden_UK
dc.type.statusVoR - Version of Recorden_UK
dc.author.emailbrian.austin@stir.ac.uken_UK
dc.publisher.addressOxford, UKen_UK
dc.contributor.affiliationHeriot-Watt Universityen_UK
dc.contributor.affiliationInstitute of Aquacultureen_UK
dc.identifier.isiWOS:000273310700030en_UK
dc.identifier.wtid793034en_UK
dcterms.dateAccepted2010-02-28en_UK
dc.date.filedepositdate2012-08-06en_UK
rioxxterms.typeJournal Article/Reviewen_UK
rioxxterms.versionVoRen_UK
local.rioxx.authorNya, Elijah Jacob|en_UK
local.rioxx.authorAustin, Brian|en_UK
local.rioxx.projectInternal Project|University of Stirling|https://isni.org/isni/0000000122484331en_UK
local.rioxx.freetoreaddate2999-12-29en_UK
local.rioxx.licencehttp://www.rioxx.net/licenses/under-embargo-all-rights-reserved||en_UK
local.rioxx.filenameaustin_lipopolysaccharide_2009.pdfen_UK
local.rioxx.filecount1en_UK
local.rioxx.source1364-5072en_UK
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