STORRE
STORRE: Stirling Online Research Repository
http://hdl.handle.net/1893/7208| Appears in Collections: | Biological and Environmental Sciences Journal Articles |
| Peer Review Status: | Refereed |
| Title: | Field trial of a genetically improved baculovirus insecticide |
| Author(s): | Cory, Jennifer S Hirst, Mark L Williams, Trevor Hails, Rosemary S Goulson, Dave Green, Bernadette M Carty, Timothy M Possee, Robert D Cayley, P Jane Bishop, David H L |
| Contact Email: | dave.goulson@stir.ac.uk |
| Issue Date: | 14-Jul-1994 |
| Date Deposited: | 1-Aug-2012 |
| Citation: | Cory JS, Hirst ML, Williams T, Hails RS, Goulson D, Green BM, Carty TM, Possee RD, Cayley PJ & Bishop DHL (1994) Field trial of a genetically improved baculovirus insecticide. Nature, 370 (6485), pp. 138-140. https://doi.org/10.1038/370138a0 |
| Abstract: | IMPROVEMENT of biological pesticides through genetic modification has enormous potential and the insect baculoviruses are particularly amenable to this approach1,2. A key aim of genetic engineering is to increase their speed of kill, primarily by the incorporation of genes which encode arthropod or bacterially derived insect-selective toxins3–11, insect hormones12,13 or enzymes14,15. We report here the first, to our knowledge, field trial of a genetically improved nuclear polyhedrosis virus of the alfalfa looper, Autogmpha californica (AcNPV) that expresses an insectselective toxin gene (AaHIT) derived from the venom of the scorpion Androclonus australisl6–18. Previous laboratory assays with the cabbage looper, Trichoplusia ni, demonstrated a 25% reduction in time to death compared to the wild-type virus, but unaltered pathogenicity6 and host range19. In the field, the modified baculovirus killed faster, resulting in reduced crop damage and it appeared to reduce the secondary cycle of infection compared to the wild-type virus. |
| DOI Link: | 10.1038/370138a0 |
| Rights: | The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study. |
| Licence URL(s): | http://www.rioxx.net/licenses/under-embargo-all-rights-reserved |
| File | Description | Size | Format | |
|---|---|---|---|---|
| cory_nature_1994.pdf | Fulltext - Published Version | 966 kB | Adobe PDF | Under Embargo until 2999-12-15 Request a copy |
Note: If any of the files in this item are currently embargoed, you can request a copy directly from the author by clicking the padlock icon above. However, this facility is dependent on the depositor still being contactable at their original email address.
This item is protected by original copyright |
Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.
The metadata of the records in the Repository are available under the CC0 public domain dedication: No Rights Reserved https://creativecommons.org/publicdomain/zero/1.0/
If you believe that any material held in STORRE infringes copyright, please contact library@stir.ac.uk providing details and we will remove the Work from public display in STORRE and investigate your claim.