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dc.contributor.authorBekaert, Michaël-
dc.contributor.authorFirth, Andrew E-
dc.contributor.authorZhang, Yan-
dc.contributor.authorGladyshev, Vadim N-
dc.contributor.authorAtkins, John F-
dc.contributor.authorBaranov, Pavel V-
dc.description.abstract'Recoding' is a term used to describe non-standard read-out of the genetic code, and encompasses such phenomena as programmed ribosomal frameshifting, stop codon readthrough, selenocysteine insertion and translational bypassing. Although only a small proportion of genes utilize recoding in protein synthesis, accurate annotation of ‘recoded’ genes lags far behind annotation of 'standard' genes. In order to address this issue, provide a service to researchers in the field, and offer training data for developers of gene-annotation software, we have gathered together known cases of recoding within the Recode database. Recode-2 is an improved and updated version of the database. It provides access to detailed information on genes known to utilize translational recoding and allows complex search queries, browsing of recoding data and enhanced visualization of annotated sequence elements. At present, the Recode-2 database stores information on approximately 1500 genes that are known to utilize recoding in their expression—a factor of approximately three increase over the previous version of the database. Recode-2 is available at http://recode.ucc.ieen_UK
dc.publisherOxford University Press-
dc.relationBekaert M, Firth AE, Zhang Y, Gladyshev VN, Atkins JF & Baranov PV (2010) Recode-2: new design, new search tools, and many more genes, Nucleic Acids Research, 38 (Supplement 1), pp. D69-D74.-
dc.rightsPublisher policy allows this work to be made available in this repository. Published in Nucleic Acids Research by Oxford University Press. Nucleic Acids Research (2010) 38 (suppl 1): D69-D74.
dc.titleRecode-2: new design, new search tools, and many more genesen_UK
dc.typeJournal Articleen_UK
dc.citation.jtitleNucleic Acids Research-
dc.citation.issueSupplement 1-
dc.type.statusPublisher version (final published refereed version)-
dc.contributor.affiliationUniversity College Cork-
dc.contributor.affiliationHarvard Medical School-
dc.contributor.affiliationHarvard Medical School-
dc.contributor.affiliationUniversity of Utah-
dc.contributor.affiliationUniversity College Cork-
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