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Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/38344
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dc.contributor.authorJuhász, Alexandraen_UK
dc.contributor.authorMakaula, Peteren_UK
dc.contributor.authorCunningham, Lucas Jen_UK
dc.contributor.authorNkolokosa, Clintonen_UK
dc.contributor.authorArcher, Johnen_UK
dc.contributor.authorJones, Samen_UK
dc.contributor.authorNamacha, Gladysen_UK
dc.contributor.authorChammudzi, Priscillaen_UK
dc.contributor.authorMainga, Brighten_UK
dc.contributor.authorLally, Daviden_UK
dc.contributor.authorKayuni, Sekeleghe Aen_UK
dc.contributor.authorLaCourse, E Jamesen_UK
dc.contributor.authorO'Ferrall, Angus Men_UK
dc.contributor.authorMusaya, Janelisaen_UK
dc.contributor.authorStothard, J Russellen_UK
dc.date.accessioned2026-09-19T00:04:56Z-
dc.date.available2026-09-19T00:04:56Z-
dc.date.issued2026-01-08en_UK
dc.identifier.urihttp://hdl.handle.net/1893/38344-
dc.description.abstractSchistosoma mattheei is a zoonotic schistosome species in central and southern Africa and is of increasing public health concern in southern Malawi. To gain insight into its local transmission, we investigated the biology of Schistosoma mattheei in southern Malawi, integrating epidemiological, environmental and genetic data within a One Health framework. Cattle, goats, humans and snails were surveyed, with DNA barcoding revealing nine mitochondrial S. mattheei haplotypes. Two haplotypes were shared across species, indicating cross-host transmission. Infected snails were detected year-round, with seasonal variation linked to vegetation cover (Normalized Difference Vegetation Index (NDVI)). Praziquantel (40 mg kg−1) treatment in selected cattle herds reduced infection prevalence over 12 weeks. These findings highlight the zoonotic potential of S. mattheei and the need for integrated control strategies.en_UK
dc.language.isoenen_UK
dc.publisherThe Royal Societyen_UK
dc.relationJuhász A, Makaula P, Cunningham LJ, Nkolokosa C, Archer J, Jones S, Namacha G, Chammudzi P, Mainga B, Lally D, Kayuni SA, LaCourse EJ, O'Ferrall AM, Musaya J & Stothard JR (2026) One Health insights into local transmission of zoonotic Schistosoma mattheei in southern Malawi. <i>Philosophical Transactions B</i>, 381 (1941). https://doi.org/10.1098/rstb.2024.0519en_UK
dc.rightsPublished by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are crediteden_UK
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_UK
dc.subjectschistosomiasisen_UK
dc.subjectmicroepidemiologyen_UK
dc.subjectDNA barcodingen_UK
dc.subjecthybridizationen_UK
dc.subjectlivestocken_UK
dc.subjectnormalized difference vegetation indexen_UK
dc.titleOne Health insights into local transmission of zoonotic Schistosoma mattheei in southern Malawien_UK
dc.typeJournal Articleen_UK
dc.identifier.doi10.1098/rstb.2024.0519en_UK
dc.identifier.pmid41538080en_UK
dc.citation.jtitlePhilosophical Transactions of the Royal Society B: Biological Sciencesen_UK
dc.citation.issn1471-2970en_UK
dc.citation.issn0962-8436en_UK
dc.citation.volume381en_UK
dc.citation.issue1941en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedRefereeden_UK
dc.type.statusVoR - Version of Recorden_UK
dc.contributor.funderThe Wellcome Trusten_UK
dc.author.emailclinton.nkolokosa@stir.ac.uken_UK
dc.citation.date08/01/2026en_UK
dc.contributor.affiliationLiverpool School of Tropical Medicineen_UK
dc.contributor.affiliationMalawi-Liverpool Wellcome Trust Clinical Research Programmeen_UK
dc.contributor.affiliationLiverpool School of Tropical Medicineen_UK
dc.contributor.affiliationBiological and Environmental Sciencesen_UK
dc.contributor.affiliationLiverpool School of Tropical Medicineen_UK
dc.contributor.affiliationLiverpool School of Tropical Medicineen_UK
dc.contributor.affiliationMalawi-Liverpool Wellcome Trust Clinical Research Programmeen_UK
dc.contributor.affiliationMalawi-Liverpool Wellcome Trust Clinical Research Programmeen_UK
dc.contributor.affiliationMalawi-Liverpool Wellcome Trust Clinical Research Programmeen_UK
dc.contributor.affiliationMalawi-Liverpool Wellcome Trust Clinical Research Programmeen_UK
dc.contributor.affiliationLiverpool School of Tropical Medicineen_UK
dc.contributor.affiliationLiverpool School of Tropical Medicineen_UK
dc.contributor.affiliationLiverpool School of Tropical Medicineen_UK
dc.contributor.affiliationMalawi-Liverpool Wellcome Trust Clinical Research Programmeen_UK
dc.contributor.affiliationLiverpool School of Tropical Medicineen_UK
dc.identifier.scopusid105027705344en_UK
dc.identifier.wtid2296102en_UK
dc.contributor.orcid0000-0003-2600-3544en_UK
dc.contributor.orcid0000-0002-3017-4074en_UK
dc.contributor.orcid0000-0002-5190-7302en_UK
dc.contributor.orcid0009-0008-2800-208Xen_UK
dc.contributor.orcid0000-0002-6948-0087en_UK
dc.contributor.orcid0000-0003-1077-968Xen_UK
dc.contributor.orcid0000-0003-2928-0133en_UK
dc.contributor.orcid0000-0002-9370-3420en_UK
dc.date.accepted2025-09-22en_UK
dcterms.dateAccepted2025-09-22en_UK
dc.date.filedepositdate2026-09-10en_UK
rioxxterms.apcnot requireden_UK
rioxxterms.versionVoRen_UK
local.rioxx.authorJuhász, Alexandra|0000-0003-2600-3544en_UK
local.rioxx.authorMakaula, Peter|en_UK
local.rioxx.authorCunningham, Lucas J|0000-0002-3017-4074en_UK
local.rioxx.authorNkolokosa, Clinton|0000-0002-5190-7302en_UK
local.rioxx.authorArcher, John|en_UK
local.rioxx.authorJones, Sam|en_UK
local.rioxx.authorNamacha, Gladys|en_UK
local.rioxx.authorChammudzi, Priscilla|en_UK
local.rioxx.authorMainga, Bright|en_UK
local.rioxx.authorLally, David|0009-0008-2800-208Xen_UK
local.rioxx.authorKayuni, Sekeleghe A|0000-0002-6948-0087en_UK
local.rioxx.authorLaCourse, E James|en_UK
local.rioxx.authorO'Ferrall, Angus M|0000-0003-1077-968Xen_UK
local.rioxx.authorMusaya, Janelisa|0000-0003-2928-0133en_UK
local.rioxx.authorStothard, J Russell|0000-0002-9370-3420en_UK
local.rioxx.projectProject ID unknown|The Wellcome Trust|en_UK
local.rioxx.freetoreaddate2026-09-18en_UK
local.rioxx.licencehttp://creativecommons.org/licenses/by/4.0/|2026-09-18|en_UK
local.rioxx.filenamerstb.2024.0519.pdfen_UK
local.rioxx.filecount1en_UK
local.rioxx.source1471-2970en_UK
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