Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/35629
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dc.contributor.authorMurchie, Peteren_UK
dc.contributor.authorMasthoff, Judithen_UK
dc.contributor.authorWalter, Fiona Men_UK
dc.contributor.authorRahman, Kazien_UK
dc.contributor.authorAllan, Julia Len_UK
dc.contributor.authorBurrows, Nigelen_UK
dc.contributor.authorProby, Charlotteen_UK
dc.contributor.authorLee, Amanda Jen_UK
dc.contributor.authorJohnston, Marieen_UK
dc.contributor.authorDurrani, Ameren_UK
dc.contributor.authorDepasquale, Ivanen_UK
dc.contributor.authorBrant, Billyen_UK
dc.contributor.authorNeilson, Aileenen_UK
dc.contributor.authorMeredith, Fionaen_UK
dc.contributor.authorTreweek, Shaun Pen_UK
dc.date.accessioned2023-11-30T01:18:51Z-
dc.date.available2023-11-30T01:18:51Z-
dc.date.issued2019-06-03en_UK
dc.identifier.other318en_UK
dc.identifier.urihttp://hdl.handle.net/1893/35629-
dc.description.abstractBackground Melanoma is common; 15,906 people in the UK were diagnosed with melanoma in 2015 and incidence has increased fivefold in 30 years. Melanoma affects old and young people, with poor prognosis once metastatic. UK guidelines recommend people treated for cutaneous melanoma receive extended outpatient, hospital follow up to detect recurrence or new primaries. Such follow up of the growing population of melanoma survivors is burdensome for both individuals and health services. Follow up is important since approximately 20% of patients with early-stage melanoma experience a recurrence and 4–8% develop a new primary; the risk of either is highest in the first 5 years. Achieving Self-directed Integrated Cancer Aftercare (ASICA) is a digital intervention to increase total-skin-self-examination (TSSE) by people treated for melanoma, with usual follow up. Methods We aim to recruit 240 adults with a previous first-stage 0-2C primary cutaneous melanoma, from secondary care in North-East Scotland and the East of England. Participants will be randomised to receive the ASICA intervention (a tablet-based digital intervention to prompt and support TSSE) or control group (treatment as usual). Patient-reported and clinical data will be collected at baseline, including the modified Melanoma Worry Scale (MWS), the Hospital Anxiety and Depression Scale (HADs), the EuroQoL 5-dimension 5-level questionnaire (EQ-5D-5 L), and questions about TSSE practice, intentions, self-efficacy and planning. Participants will be followed up by postal questionnaire at 3, 6 and 12 months following randomization, along with a 12-month review of clinical data. The primary timepoint for outcome analyses will be12 months after randomisation. Discussion If the ASICA intervention improves the practice of TSSE in those affected by melanoma, this may lead to improved psychological well-being and earlier detection of recurrent and new primary melanoma. This could impact both patients and National Health Service (NHS) resources. This study will determine if a full-scale randomised controlled trial can be undertaken in the UK NHS to provide the high-quality evidence needed to determine the effectiveness of the intervention. ASICA is a pilot study evaluating the effectiveness of the practice of digitally supported TSSE in those affected by melanoma. Trial registration Clinical Trials.gov, NCT03328247. Registered on 1 November 2017.en_UK
dc.language.isoenen_UK
dc.publisherBioMed Centralen_UK
dc.relationMurchie P, Masthoff J, Walter FM, Rahman K, Allan JL, Burrows N, Proby C, Lee AJ, Johnston M, Durrani A, Depasquale I, Brant B, Neilson A, Meredith F & Treweek SP (2019) Achieving Self-Directed Integrated Cancer Aftercare (ASICA) in melanoma: Protocol for a randomised patient-focused pilot trial of delivering the ASICA intervention as a means to earlier detection of recurrent and second primary melanoma. <i>Trials</i>, 20, Art. No.: 318. https://doi.org/10.1186/s13063-019-3453-xen_UK
dc.rightsThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.en_UK
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_UK
dc.subjectPrimary careen_UK
dc.subjectMelanomaen_UK
dc.subjectCanceren_UK
dc.subjectRandomised controlled trialen_UK
dc.subjectSurvivorshipen_UK
dc.subjectSelf-directed careen_UK
dc.subjecte-healthen_UK
dc.subjectASICAen_UK
dc.titleAchieving Self-Directed Integrated Cancer Aftercare (ASICA) in melanoma: Protocol for a randomised patient-focused pilot trial of delivering the ASICA intervention as a means to earlier detection of recurrent and second primary melanomaen_UK
dc.typeJournal Articleen_UK
dc.identifier.doi10.1186/s13063-019-3453-xen_UK
dc.identifier.pmid31159849en_UK
dc.citation.jtitleTrialsen_UK
dc.citation.issn1745-6215en_UK
dc.citation.volume20en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedRefereeden_UK
dc.type.statusVoR - Version of Recorden_UK
dc.contributor.funderCancer Research UKen_UK
dc.author.emailjulia.allan@stir.ac.uken_UK
dc.citation.date03/06/2019en_UK
dc.description.notesAdditional authors: S. Hall & A. McDonalden_UK
dc.contributor.affiliationUniversity of Aberdeenen_UK
dc.contributor.affiliationUniversity of Aberdeenen_UK
dc.contributor.affiliationUniversity of Cambridgeen_UK
dc.contributor.affiliationNHS Grampianen_UK
dc.contributor.affiliationUniversity of Aberdeenen_UK
dc.contributor.affiliationCambridge University Hospitals NHSen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationUniversity of Aberdeenen_UK
dc.contributor.affiliationUniversity of Aberdeenen_UK
dc.contributor.affiliationCambridge University Hospitals NHSen_UK
dc.contributor.affiliationNHS Grampianen_UK
dc.contributor.affiliationNHS Grampianen_UK
dc.contributor.affiliationUniversity of Aberdeenen_UK
dc.contributor.affiliationNHS Grampianen_UK
dc.contributor.affiliationUniversity of Aberdeenen_UK
dc.identifier.isiWOS:000470254100002en_UK
dc.identifier.scopusid2-s2.0-85066830276en_UK
dc.identifier.wtid1935667en_UK
dc.contributor.orcid0000-0001-7287-8363en_UK
dc.date.accepted2019-05-18en_UK
dcterms.dateAccepted2019-05-18en_UK
dc.date.filedepositdate2023-11-20en_UK
rioxxterms.apcnot requireden_UK
rioxxterms.typeJournal Article/Reviewen_UK
rioxxterms.versionVoRen_UK
local.rioxx.authorMurchie, Peter|en_UK
local.rioxx.authorMasthoff, Judith|en_UK
local.rioxx.authorWalter, Fiona M|en_UK
local.rioxx.authorRahman, Kazi|en_UK
local.rioxx.authorAllan, Julia L|0000-0001-7287-8363en_UK
local.rioxx.authorBurrows, Nigel|en_UK
local.rioxx.authorProby, Charlotte|en_UK
local.rioxx.authorLee, Amanda J|en_UK
local.rioxx.authorJohnston, Marie|en_UK
local.rioxx.authorDurrani, Amer|en_UK
local.rioxx.authorDepasquale, Ivan|en_UK
local.rioxx.authorBrant, Billy|en_UK
local.rioxx.authorNeilson, Aileen|en_UK
local.rioxx.authorMeredith, Fiona|en_UK
local.rioxx.authorTreweek, Shaun P|en_UK
local.rioxx.projectProject ID unknown|Cancer Research UK|http://dx.doi.org/10.13039/501100000289en_UK
local.rioxx.freetoreaddate2023-11-20en_UK
local.rioxx.licencehttp://creativecommons.org/licenses/by/4.0/|2023-11-20|en_UK
local.rioxx.filenames13063-019-3453-x.pdfen_UK
local.rioxx.filecount1en_UK
local.rioxx.source1745-6215en_UK
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