Dietary supplementation of β-glucan improves growth performance, the innate immune response and stress resistance of red sea bream,Pagrus major

Abstract

A 56-day feeding trial was conducted to evaluate the effects of supplemented diets with β-glucan (BG) at four levels [0 (D1), 250 (D2), 500 (D3) and 1000 (D4) mg BG kg−1] on red sea bream, Pagrus major. The obtained results revealed a significant increase (P < 0.05) in final body weight, weight gain, specific growth rate, feed intake, body protein content, lysozyme activity and tolerance against low-salinity stress test in all BG-supplemented groups when compared with BG-free group. Furthermore, D4 group resulted in a significant increase in feed efficiency ratio, protein gain, protein and lipid digestibilities, serum bactericidal activity and peroxidase content when compared with D1 group (P < 0.05). Haematocrit and plasma protein content in D3 group were significantly higher than those in D1 group (P < 0.05). Interestingly, BG supplementation decreased glutamic oxaloacetic transaminase (GOT) in D2 group and reactive oxygen metabolites in D2, D3 and D4 groups when compared with D1 group. Following low-salinity stress test, significantly higher amounts of secreted mucus were observed in fish fed D2 and D4 diets than those from fish fed D1 diet (P < 0.05). In conclusion, the supplementation of BG improves growth, stress resistance and immune response of P. major.