Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/33779
Appears in Collections:Psychology Journal Articles
Peer Review Status: Refereed
Title: Consensus Paper: Novel Directions and Next Steps of Non-invasive Brain Stimulation of the Cerebellum in Health and Disease
Author(s): Manto, Mario
Argyropoulos, Georgios P D
Bocci, Tommaso
Celnik, Pablo A
Corben, Louise A
Guidetti, Matteo
Koch, Giacomo
Priori, Alberto
Rothwell, John C
Sadnicka, Anna
Spampinato, Danny
Ugawa, Yoshikazu
Wessel, Maximilian J
Ferrucci, Roberta
Contact Email: georgios.argyropoulos@stir.ac.uk
Keywords: Cerebellum
Neuromodulation
Non-invasive
tDCS
TMS
Issue Date: 23-Nov-2021
Date Deposited: 5-Jan-2022
Citation: Manto M, Argyropoulos GPD, Bocci T, Celnik PA, Corben LA, Guidetti M, Koch G, Priori A, Rothwell JC, Sadnicka A, Spampinato D, Ugawa Y, Wessel MJ & Ferrucci R (2021) Consensus Paper: Novel Directions and Next Steps of Non-invasive Brain Stimulation of the Cerebellum in Health and Disease. Cerebellum. https://doi.org/10.1007/s12311-021-01344-6
Abstract: The cerebellum is involved in multiple closed-loops circuitry which connect the cerebellar modules with the motor cortex, prefrontal, temporal, and parietal cortical areas, and contribute to motor control, cognitive processes, emotional processing, and behavior. Among them, the cerebello-thalamo-cortical pathway represents the anatomical substratum of cerebellum-motor cortex inhibition (CBI). However, the cerebellum is also connected with basal ganglia by disynaptic pathways, and cerebellar involvement in disorders commonly associated with basal ganglia dysfunction (e.g., Parkinson’s disease and dystonia) has been suggested. Lately, cerebellar activity has been targeted by non-invasive brain stimulation (NIBS) techniques including transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) to indirectly affect and tune dysfunctional circuitry in the brain. Although the results are promising, several questions remain still unsolved. Here, a panel of experts from different specialties (neurophysiology, neurology, neurosurgery, neuropsychology) reviews the current results on cerebellar NIBS with the aim to derive the future steps and directions needed. We discuss the effects of TMS in the field of cerebellar neurophysiology, the potentials of cerebellar tDCS, the role of animal models in cerebellar NIBS applications, and the possible application of cerebellar NIBS in motor learning, stroke recovery, speech and language functions, neuropsychiatric and movement disorders.
DOI Link: 10.1007/s12311-021-01344-6
Rights: This item has been embargoed for a period. During the embargo please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study. This is a post-peer-review, pre-copyedit version of an article published in The Cerebellum. The final authenticated version is available online at: https://doi.org/10.1007/s12311-021-01344-6
Notes: Output Status: Forthcoming/Available Online
Licence URL(s): https://storre.stir.ac.uk/STORREEndUserLicence.pdf

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