STORRE
STORRE: Stirling Online Research Repository
Please use this identifier to cite or link to this item:
http://hdl.handle.net/1893/33661| Appears in Collections: | Biological and Environmental Sciences Journal Articles |
| Peer Review Status: | Refereed |
| Title: | Propionic Acid Promotes the Virulent Phenotype of Crohn’s Disease-Associated Adherent-Invasive Escherichia coli |
| Author(s): | Ormsby, Michael J Johnson, Síle A Carpena, Nuria Meikle, Lynsey M Goldstone, Robert J McIntosh, Anne Wessel, Hannah M Hulme, Heather E McConnachie, Ceilidh C Connolly, James P R Roe, Andrew J Hasson, Conor Boyd, Joseph Fitzgerald, Eamonn Gerasimidis, Konstantinos |
| Contact Email: | michael.ormsby1@stir.ac.uk |
| Keywords: | Crohn's disease adherent-invasive E. coli propionic acid short chain fatty acid |
| Issue Date: | Feb-2020 |
| Date Deposited: | 25-Nov-2021 |
| Citation: | Ormsby MJ, Johnson SA, Carpena N, Meikle LM, Goldstone RJ, McIntosh A, Wessel HM, Hulme HE, McConnachie CC, Connolly JPR, Roe AJ, Hasson C, Boyd J, Fitzgerald E & Gerasimidis K (2020) Propionic Acid Promotes the Virulent Phenotype of Crohn’s Disease-Associated Adherent-Invasive Escherichia coli. Cell Reports, 30 (7), pp. 2297-2305.e5. https://doi.org/10.1016/J.CELREP.2020.01.078 |
| Abstract: | The short chain fatty acid propionic acid is a bacterium-derived human intestinal antimicrobial and immune modulator used widely in Western food production and agriculture. Here, Ormsby et al. demonstrate that exposure to propionic acid induces virulence-associated phenotypic changes in Crohn's disease-associated adherent-invasive Escherichia coli (AIEC). |
| DOI Link: | 10.1016/J.CELREP.2020.01.078 |
| Rights: | © 2020 The Author(s). This is an open access article distributed under the terms of the Creative Commons CC-BY license (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You are not required to obtain permission to reuse this article. |
| Notes: | Additional co-authors: Douglas Morrison, Georgina L. Hold, Richard Hansen, Daniel Walker, David G.E. Smith, Daniel M. Wall |
| Licence URL(s): | http://creativecommons.org/licenses/by/4.0/ |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| PIIS2211124720301030.pdf | Fulltext - Published Version | 2.26 MB | Adobe PDF | View/Open |
This item is protected by original copyright |
A file in this item is licensed under a Creative Commons License
Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.
The metadata of the records in the Repository are available under the CC0 public domain dedication: No Rights Reserved https://creativecommons.org/publicdomain/zero/1.0/
If you believe that any material held in STORRE infringes copyright, please contact library@stir.ac.uk providing details and we will remove the Work from public display in STORRE and investigate your claim.