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dc.contributor.authorBueno de Mesquita, Clifton Pen_UK
dc.contributor.authorNichols, Lauren Men_UK
dc.contributor.authorGebert, Matthew Jen_UK
dc.contributor.authorVanderburgh, Caihongen_UK
dc.contributor.authorBocksberger, Gaëlleen_UK
dc.contributor.authorLester, Jack Den_UK
dc.contributor.authorKalan, Ammie Ken_UK
dc.contributor.authorDieguez, Paulaen_UK
dc.contributor.authorMcCarthy, Maureen Sen_UK
dc.contributor.authorAgbor, Anthonyen_UK
dc.contributor.authorÁlvarez Varona, Paulaen_UK
dc.contributor.authorAyimisin, Ayuk Emmanuelen_UK
dc.contributor.authorBessone, Mattiaen_UK
dc.contributor.authorChancellor, Rebeccaen_UK
dc.contributor.authorJeffery, Kathryn Jen_UK
dc.description.abstractUnderstanding variation in host-associated microbial communities is important given the relevance of microbiomes to host physiology and health. Using 560 fecal samples collected from wild chimpanzees (Pan troglodytes) across their range, we assessed how geography, genetics, climate, vegetation, and diet relate to gut microbial community structure (prokaryotes, eukaryotic parasites) at multiple spatial scales. We observed a high degree of regional specificity in the microbiome composition, which was associated with host genetics, available plant foods, and potentially with cultural differences in tool use, which affect diet. Genetic differences drove community composition at large scales, while vegetation and potentially tool use drove within-region differences, likely due to their influence on diet. Unlike industrialized human populations in the United States, where regional differences in the gut microbiome are undetectable, chimpanzee gut microbiomes are far more variable across space, suggesting that technological developments have decoupled humans from their local environments, obscuring regional differences that could have been important during human evolution.en_UK
dc.publisherAmerican Society for Microbiologyen_UK
dc.relationBueno de Mesquita CP, Nichols LM, Gebert MJ, Vanderburgh C, Bocksberger G, Lester JD, Kalan AK, Dieguez P, McCarthy MS, Agbor A, Álvarez Varona P, Ayimisin AE, Bessone M, Chancellor R & Jeffery KJ (2021) Structure of Chimpanzee Gut Microbiomes across Tropical Africa. mSystems, 6 (3), Art. No.: e01269-20.
dc.rights© 2021 Bueno de Mesquita et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (
dc.subjecthost geneticsen_UK
dc.titleStructure of Chimpanzee Gut Microbiomes across Tropical Africaen_UK
dc.typeJournal Articleen_UK
dc.type.statusVoR - Version of Recorden_UK
dc.contributor.funderHeinz L. Krekeler Foundationen_UK
dc.contributor.funderMax Planck Society Innovation Funden_UK
dc.contributor.funderMax Planck Societyen_UK
dc.contributor.funderDeutsche Forschungsgemeinschaften_UK
dc.description.notesAdditional co-authors: Heather Cohen, Charlotte Coupland, Tobias Deschner, Villard Ebot Egbe, Annemarie Goedmakers, Anne-Céline Granjon, Cyril C. Grueter, Josephine Head, R. Adriana Hernandez-Aguilar, Sorrel Jones, Parag Kadam, Michael Kaiser, Juan Lapuente, Bradley Larson, Sergio Marrocoli, David Morgan, Badru Mugerwa, Felix Mulindahabi, Emily Neil, Protais Niyigaba, Liliana Pacheco, Alex K. Piel, Martha M. Robbins, Aaron Rundus, Crickette M. Sanz, Lilah Sciaky, Douglas Sheil, Volker Sommer, Fiona A. Stewart, Els Ton, Joost van Schijndel, Virginie Vergnes, Erin G. Wessling, Roman M. Wittig, Yisa Ginath Yuh, Kyle Yurkiw, Klaus Zuberbühler, Jan F. Gogarten, Anna Heintz-Buschart, Alexandra N. Muellner-Riehl, Christophe Boesch, Hjalmar S. Kühl, Noah Fierer, Mimi Arandjelovic, Robert R. Dunnen_UK
dc.contributor.affiliationUniversity of Colorado Boulderen_UK
dc.contributor.affiliationNorth Carolina State Universityen_UK
dc.contributor.affiliationUniversity of Colorado Boulderen_UK
dc.contributor.affiliationUniversity of Colorado Boulderen_UK
dc.contributor.affiliationMax Planck Institute for Evolutionary Anthropologyen_UK
dc.contributor.affiliationMax Planck Institute for Evolutionary Anthropologyen_UK
dc.contributor.affiliationMax Planck Institute for Evolutionary Anthropologyen_UK
dc.contributor.affiliationMax Planck Institute for Evolutionary Anthropologyen_UK
dc.contributor.affiliationMax Planck Institute for Evolutionary Anthropologyen_UK
dc.contributor.affiliationMax Planck Institute for Evolutionary Anthropologyen_UK
dc.contributor.affiliationJane Goodall Instituteen_UK
dc.contributor.affiliationMax Planck Institute for Evolutionary Anthropologyen_UK
dc.contributor.affiliationMax Planck Institute for Evolutionary Anthropologyen_UK
dc.contributor.affiliationWest Chester University, Pennsylvaniaen_UK
dc.contributor.affiliationBiological and Environmental Sciencesen_UK
rioxxterms.apcnot requireden_UK
rioxxterms.typeJournal Article/Reviewen_UK
local.rioxx.authorBueno de Mesquita, Clifton P|0000-0002-2565-7100en_UK
local.rioxx.authorNichols, Lauren M|en_UK
local.rioxx.authorGebert, Matthew J|en_UK
local.rioxx.authorVanderburgh, Caihong|en_UK
local.rioxx.authorBocksberger, Gaëlle|en_UK
local.rioxx.authorLester, Jack D|en_UK
local.rioxx.authorKalan, Ammie K|en_UK
local.rioxx.authorDieguez, Paula|en_UK
local.rioxx.authorMcCarthy, Maureen S|en_UK
local.rioxx.authorAgbor, Anthony|en_UK
local.rioxx.authorÁlvarez Varona, Paula|en_UK
local.rioxx.authorAyimisin, Ayuk Emmanuel|en_UK
local.rioxx.authorBessone, Mattia|en_UK
local.rioxx.authorChancellor, Rebecca|en_UK
local.rioxx.authorJeffery, Kathryn J|0000-0002-2632-0008en_UK
local.rioxx.projectProject ID unknown|Heinz L. Krekeler Foundation|en_UK
local.rioxx.projectProject ID unknown|Max Planck Society Innovation Fund|en_UK
local.rioxx.projectProject ID unknown|Max Planck Society|en_UK
local.rioxx.projectFOR2136|Deutsche Forschungsgemeinschaft|en_UK
Appears in Collections:Biological and Environmental Sciences Journal Articles

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