|Appears in Collections:||Aquaculture Journal Articles|
|Peer Review Status:||Refereed|
|Title:||The Whole-Genome Sequencing and Hybrid Assembly of Mytilus coruscus|
genome assembly and annotation
|Citation:||Li R, Zhang W, Lu J, Zhang Z, Mu C, Song W, Migaud H, Wang C & Bekaert M (2020) The Whole-Genome Sequencing and Hybrid Assembly of Mytilus coruscus. Frontiers in Genetics, 11, Art. No.: 440. https://doi.org/10.3389/fgene.2020.00440|
|Abstract:||The hard-shelled mussel (Mytilus coruscus) is an economically important shellfish, which has been cultivated for the last decade. Due to over-exploitation, most mussel stocks have dramatically declined. Efforts to study this species' natural distribution, genetics, breeding and cultivation have been hindered by the lack of a high-quality reference genome. To address this, we produced a hybrid high-quality reference genome of M. coruscus using a long-read platform to assemble the genome and short-reads, high-quality technology to accurately correct for sequence errors. The genome was assembled into 10,484 scaffolds, a total length of 1.90 Gb and a scaffold N50 of 898 kb. Ab initio annotation of the M. coruscus genome assembly identified a total of 42,684 genes. This accurate, reference genome of M. coruscus provides an essential resource with the advantage of enabling the genome-scale selective breeding of M. coruscus. More importantly it will also help the deciphering of the speciation and local adaptation of the Mytilus species.|
|Rights:||© 2020 Li, Zhang, Lu, Zhang, Mu, Song, Migaud, Wang and Bekaert. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY - https://creativecommons.org/licenses/by/4.0/). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.|
|fgene-11-00440.pdf||Fulltext - Published Version||1.05 MB||Adobe PDF||View/Open|
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