|Appears in Collections:||Psychology Journal Articles|
|Peer Review Status:||Refereed|
|Title:||Major histocompatibility complex-associated odour preferences and human mate choice: near and far horizons|
Roberts, S Craig
|Citation:||Havlicek J, Winternitz J & Roberts SC (2020) Major histocompatibility complex-associated odour preferences and human mate choice: near and far horizons. Philosophical Transactions of the Royal Society B: Biological Sciences, 375 (1800), Art. No.: 20190260. https://doi.org/10.1098/rstb.2019.0260|
|Abstract:||The major histocompatibility complex (MHC) is a core part of the adaptive immune system. As in other vertebrate taxa, it may also affect human chemical communication via odour-based mate preferences, with greater attraction towards MHC-dissimilar partners. However, despite some well-known findings, the available evidence is equivocal and made complicated by varied approaches to quantifying human mate choice. To address this, we here conduct comprehensive meta-analyses focusing on studies assessing i] genomic mate selection, ii] relationship satisfaction and iii] odour preference. Analysis of genomic studies reveals no association between MHC-dissimilarity and mate choice in actual couples; however, MHC effects appear to be independent of genomic background. The effect of MHC-dissimilarity on relationship satisfaction was not significant and we found evidence for publication bias in studies on this area. There was also no significant association between MHC-dissimilarity and odour preferences. Finally, combining effect sizes from all genomic, relationship satisfaction, odour preference and previous mate choice studies into an overall estimate showed no overall significant effect of MHC similarity on human mate selection. Based on these findings, we make a set of recommendations for future studies, focusing both on aspects that should be implemented immediately and those that lurk on the far horizon. We need larger samples with greater geographical and cultural diversity, that control for genome-wide similarity. We also need more focus on mechanisms of MHC-associated odour preferences and on MHC-associated pregnancy loss.|
|Rights:||Publisher policy allows this work to be made available in this repository. Published in Philosophical Transactions of the Royal Society B: Biological Sciences. The original publication is available at: https://doi.org.10.1098/rstb.2019.0260|
|Havlicek_MHC_final accepted version.pdf||Fulltext - Accepted Version||1.3 MB||Adobe PDF||View/Open|
This item is protected by original copyright
Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.
If you believe that any material held in STORRE infringes copyright, please contact email@example.com providing details and we will remove the Work from public display in STORRE and investigate your claim.