Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/30150
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dc.contributor.authorHirst, Yaseminen_UK
dc.contributor.authorStoffel, Sandroen_UK
dc.contributor.authorBaio, Gianlucaen_UK
dc.contributor.authorMcGregor, Lesleyen_UK
dc.contributor.authorvon Wagner, Christianen_UK
dc.date.accessioned2019-09-25T00:02:45Z-
dc.date.available2019-09-25T00:02:45Z-
dc.date.issued2018-09-07en_UK
dc.identifier.urihttp://hdl.handle.net/1893/30150-
dc.description.abstractBackground The initial roll-out of the English Bowel (Colorectal) Cancer Screening programme, during 2006 and 2009, found uptake to be low (54%) and socially graded. The current analysis used data from 2010 to 2015 to test whether uptake is increasing and becoming less socially graded over time. Methods Postcode-derived area-level uptake of 4.4 million first-time invitees, stratified by gender and the year of the first invitation (2010–2015), was generated using the National Bowel Cancer Screening System. Data were limited to people aged 60–64 years. Binomial regression tested for variations in uptake by the year of invitation, gender, region, area-based socio-economic deprivation and area-based ethnic diversity. Results Overall, the first-time colorectal cancer (CRC) screening uptake across 6 years was 52% (n = 2,285,996/4,423,734) with a decline between 2010 and 2015 (53%, 54%, 52%, 50%, 49%, 49% respectively). Uptake continued to be socially graded between the most and the least deprived area-level socio-economic deprivation quintiles (43% vs 57%), the most and the least area-based ethnic diversity quintiles (41% vs 56%) and men and women (47% vs 56%). Multivariate analysis demonstrated the effects of year, deprivation, ethnicity and gender on uptake. The effect of deprivation was more pronounced in the most deprived area quintile between men and women (40% vs 47%) than the least deprived area quintile (52% vs 62% respectively). Conclusion We did not find evidence of change in uptake patterns in CRC screening since its initial launch 10 years ago. The programme is unlikely to realise its full public health benefits and is en route to widening inequalities in CRC outcomes.en_UK
dc.language.isoenen_UK
dc.publisherElsevieren_UK
dc.relationHirst Y, Stoffel S, Baio G, McGregor L & von Wagner C (2018) Uptake of the English Bowel (Colorectal) Cancer Screening Programme: an update 5 years after the full roll-out. European Journal of Cancer, 103, pp. 267-273. https://doi.org/10.1016/j.ejca.2018.07.135en_UK
dc.rightsCopyright 2018 Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)en_UK
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en_UK
dc.subjectCancer screening uptakeen_UK
dc.subjectInequalitiesen_UK
dc.subjectDiffusion of innovationen_UK
dc.titleUptake of the English Bowel (Colorectal) Cancer Screening Programme: an update 5 years after the full roll-outen_UK
dc.typeJournal Articleen_UK
dc.identifier.doi10.1016/j.ejca.2018.07.135en_UK
dc.identifier.pmid30196989en_UK
dc.citation.jtitleEuropean Journal of Canceren_UK
dc.citation.issn1365-2354en_UK
dc.citation.issn0959-8049en_UK
dc.citation.volume103en_UK
dc.citation.spage267en_UK
dc.citation.epage273en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedRefereeden_UK
dc.type.statusVoR - Version of Recorden_UK
dc.contributor.funderCancer Research UKen_UK
dc.citation.date07/09/2018en_UK
dc.contributor.affiliationUniversity College Londonen_UK
dc.contributor.affiliationUniversity College Londonen_UK
dc.contributor.affiliationUniversity College Londonen_UK
dc.contributor.affiliationUniversity College Londonen_UK
dc.contributor.affiliationUniversity College Londonen_UK
dc.identifier.isiWOS:000447292100031en_UK
dc.identifier.scopusid2-s2.0-85055173855en_UK
dc.identifier.wtid1399330en_UK
dc.contributor.orcid0000-0002-7093-1391en_UK
dc.date.accepted2018-07-22en_UK
dcterms.dateAccepted2018-07-22en_UK
dc.date.filedepositdate2019-09-19en_UK
rioxxterms.apcnot requireden_UK
rioxxterms.typeJournal Article/Reviewen_UK
rioxxterms.versionVoRen_UK
local.rioxx.authorHirst, Yasemin|en_UK
local.rioxx.authorStoffel, Sandro|en_UK
local.rioxx.authorBaio, Gianluca|en_UK
local.rioxx.authorMcGregor, Lesley|0000-0002-7093-1391en_UK
local.rioxx.authorvon Wagner, Christian|en_UK
local.rioxx.projectProject ID unknown|Cancer Research UK|http://dx.doi.org/10.13039/501100000289en_UK
local.rioxx.freetoreaddate2019-09-24en_UK
local.rioxx.licencehttp://creativecommons.org/licenses/by-nc-nd/4.0/|2019-09-24|en_UK
local.rioxx.filename1-s2.0-S0959804918311201-main.pdfen_UK
local.rioxx.filecount1en_UK
local.rioxx.source1365-2354en_UK
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