Please use this identifier to cite or link to this item:
Appears in Collections:Psychology Journal Articles
Peer Review Status: Refereed
Title: Abnormal response to negative feedback in depression
Author(s): Shah, Pallav J
O'Carroll, Ronan
Rogers, Anne
Moffoot, Anthony P R
Ebmeier, Klaus P
Keywords: Depression, Mental Case studies
Depression in old age Ability testing
Prefrontal cortex Depression
Issue Date: 1999
Date Deposited: 6-Mar-2008
Citation: Shah PJ, O'Carroll R, Rogers A, Moffoot APR & Ebmeier KP (1999) Abnormal response to negative feedback in depression. Psychological Medicine, 29 (1), pp. 63-72.
Abstract: Background. Recent studies have suggested that subjects with depression suffer a diagnosis-specific motivational deficit, characterized by an abnormal response to negative feedback that endures beyond clinical recovery. Furthermore, it has been suggested that negative feedback may motivate non-depressed controls, but not depressed patients, to improve their performance in neuropsychological tests. Methods. We describe two studies. The first compared performance on the simultaneous and delayed match to sample (SDMS) task from the CANTAB neuropsychological test battery, in 20 patients with severe depression with 20 with acute schizophrenia, 40 with chronic schizophrenia and 40 healthy controls. The second examined the performance of depressed patients with diurnal variation in symptoms and cognitive function. Results. All patients groups showed impairments on the simultaneous and delayed match to sample task compared to controls. Depressed patients did not show an abnormal response to negative feedback. Controls did not show a motivational effect of negative feedback. Depressed patients with diurnal variation showed no variation in their response to perceived failure. There was no evidence of abnormal response to negative feedback in any patient group using the ‘runs test’ or of a motivational effect in controls. Conditional probability analysis was not independent of the total number of errors made in the SDMS task. Conclusions. Further studies are suggested to examine whether an abnormal response to negative feedback characterizes particular subgroups of patients suffering from depression.
DOI Link: 10.1017/S0033291798007880
Rights: Published in Psychological Medicine. Copyright: Cambridge University Press

Files in This Item:
File Description SizeFormat 
abnormal-response-negative-feedback.pdfFulltext - Published Version289.01 kBAdobe PDFView/Open

This item is protected by original copyright

Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.

The metadata of the records in the Repository are available under the CC0 public domain dedication: No Rights Reserved

If you believe that any material held in STORRE infringes copyright, please contact providing details and we will remove the Work from public display in STORRE and investigate your claim.