Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/28100
Appears in Collections:Psychology Journal Articles
Peer Review Status: Refereed
Title: Neural and vascular responses to fused binocular stimuli: A VEP and fNIRS study
Author(s): Wijeakumar, Sobanawartiny
Shahani, Uma
McCulloch, Daphne L
Simpson, William A
Contact Email: sobanawartiny.wijeakumar@stir.ac.uk
Issue Date: Aug-2012
Citation: Wijeakumar S, Shahani U, McCulloch DL & Simpson WA (2012) Neural and vascular responses to fused binocular stimuli: A VEP and fNIRS study. Investigative Ophthalmology and Visual Science, 53 (9), pp. 5881-5889. https://doi.org/10.1167/iovs.12-10399.
Abstract: PURPOSE. The aim of our study was to investigate the correlation between neural and hemodynamic responses to stereoscopic stimuli recorded over visual cortex. METHODS. Test stimuli consisted of a static checkerboard (checks) and dichoptic static random dot (RD) presentations with no binocular disparity (ZD) or with horizontal disparity (HD). Hemodynamic responses were recorded from right and left occipital sites using functional near-infrared spectroscopy (fNIRS). Visual evoked potentials (VEPs) were recorded over three occipital sites to the onset of the same stimuli. RESULTS. Early components, N1 and P2, were sensitive to HD, suggesting that an enhanced N1-reduced P2 complex could be an indicator of binocular disparity and stereopsis. VEPs to checks and ZD stimulation were similar. fNIRS recordings showed changes in hemodynamic activation from baseline levels in response to all stimuli. In general, HD elicited a larger vascular response than ZD. Oxyhemoglobin concentration (HbO) was correlated with the VEP amplitude during the checks and HD presentations. CONCLUSIONS. We report an association between neural and hemodynamic activation in response to checks and HD. In addition, the results suggested that N1-P2 complex in the VEP could be a neural marker for stereopsis and fNIRS demonstrated differences in HbO. Specifically, checks and HD elicited larger hemodynamic responses than random dot patterns without binocular disparity.
DOI Link: 10.1167/iovs.12-10399
Rights: The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.

Files in This Item:
File Description SizeFormat 
Wijeakumar_Investigative_Ophthalmology_and_Visual_Science_August_2012.pdfFulltext - Published Version415.6 kBAdobe PDFUnder Permanent Embargo    Request a copy

Note: If any of the files in this item are currently embargoed, you can request a copy directly from the author by clicking the padlock icon above. However, this facility is dependent on the depositor still being contactable at their original email address.



This item is protected by original copyright



Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.

If you believe that any material held in STORRE infringes copyright, please contact library@stir.ac.uk providing details and we will remove the Work from public display in STORRE and investigate your claim.