Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/27840
Appears in Collections:Aquaculture Journal Articles
Peer Review Status: Refereed
Title: Effects of deoxynivalenol exposure time and contamination levels on rainbow trout
Author(s): Gonçalves, Rui A
Menanteau-Ledouble, Simon
Schöller, Mélanie
Eder, Alexander
Schmidt-Posthaus, Heike
MacKenzie, Simon
El-Matbouli, Mansour
Contact Email: sm161@stir.ac.uk
Keywords: hepatocyte hyalinization
mycotoxins
Oncorhynchus mykiss
pathogen susceptibility
Issue Date: Feb-2019
Citation: Gonçalves RA, Menanteau-Ledouble S, Schöller M, Eder A, Schmidt-Posthaus H, MacKenzie S & El-Matbouli M (2019) Effects of deoxynivalenol exposure time and contamination levels on rainbow trout. Journal of the World Aquaculture Society, 50 (1), pp. 137-154. https://doi.org/10.1111/jwas.12542
Abstract: The trend toward using plant‐based ingredients in aquafeeds is set to intensify; however, mycotoxin contamination might be a challenge. Two diets, with deoxynivalenol (DON) levels of 1,166 μg/kg (1.1 DON) and 2,745 μg/kg (2.7 DON), were prepared for short‐term DON exposure (50 days). A third diet with a low DON level of 367 μg/kg (0.3 DON) was prepared for long‐term DON exposure (168 days). Ingestion of DON by trout during both short‐term/high‐dosage exposure (50 days; 1,166 μg/kg and 2,700 μg/kg DON) and long‐term/low‐dosage exposure (168 days; 367 μg/kg DON) impacted growth performance and, to a lesser extent, liver enzyme parameters (2.7 DON). Histopathology showed mild to moderate changes in the liver but not in the other sampled tissues (intestine and kidney). Despite these effects, short‐term exposure of rainbow trout to high doses of DON did not result in increased susceptibility to Yersinia ruckeri. In both the short‐ and long‐term studies, the effects of DON showed a high interindividual variability. The present study confirms that subclinical levels of mycotoxins affect rainbow trout. The effects of such low mycotoxin levels could be masked by other production challenges while still negatively affecting productivity.
DOI Link: 10.1111/jwas.12542
Rights: This item has been embargoed for a period. During the embargo please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study. This is the peer reviewed version of the following article: Gonçalves RA, Menanteau‐Ledouble S, Schöller M, et al. Effects of deoxynivalenol exposure time and contamination levels on rainbow trout. Journal of the World Aquaculture Society 2019; 50: 137–154, which has been published in final form at https://doi.org/10.1111/jwas.12542. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for self-archiving.
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