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http://hdl.handle.net/1893/27360| Appears in Collections: | Aquaculture Journal Articles |
| Peer Review Status: | Refereed |
| Title: | Development of mobile laboratory for viral hemorrhagic fever detection in Africa |
| Author(s): | Weidmann, Manfred Faye, Ousmane Faye, Oumar Abd El Wahed, Ahmed Patel, Pranav Batejat, Christophe Manugerra, Jean Claude Adjami, Aimee Niedrig, Matthias Hufert, Frank T Sall, Amadou A |
| Contact Email: | manfred.weidmann@stir.ac.uk |
| Keywords: | Viral haemorragic fever virus Recombinase polymerase amplification SmartCycler Mobile laboratory Ebola virus disease point of care laboratory suitcase |
| Issue Date: | 15-Nov-2018 |
| Date Deposited: | 11-Jun-2018 |
| Citation: | Weidmann M, Faye O, Faye O, Abd El Wahed A, Patel P, Batejat C, Manugerra JC, Adjami A, Niedrig M, Hufert FT & Sall AA (2018) Development of mobile laboratory for viral hemorrhagic fever detection in Africa. Journal of Infectious Diseases, 218 (10), pp. 1622-1630. https://doi.org/10.1093/infdis/jiy362 |
| Abstract: | Background In order to enable local response to viral haemorrhagic fever outbreaks a mobile laboratory transportable on commercial flights was developed. Methodology The development progressed from use of mobile real time RT-PCR to mobile Recombinase Polymerase Amplification (RT-RPA). The various stages of the mobile laboratory development are described. Results A brief overview of its deployments, which culminated in the first on site detection of Ebola virus disease (EVD) in March 2014 and a successful use in a campaign to roll back EVD cases in Conakry in the West-Africa Ebola virus outbreak are described. Conclusion The developed mobile laboratory successfully enabled local teams to perform rapid viral haemorrhagic fever disgnostics. |
| DOI Link: | 10.1093/infdis/jiy362 |
| Rights: | © The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Licence URL(s): | http://creativecommons.org/licenses/by/4.0/ |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| jiy362.pdf | Fulltext - Published Version | 8.79 MB | Adobe PDF | View/Open |
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