Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorMarburger, Sarahen_UK
dc.contributor.authorAlexandrou, Markos Aen_UK
dc.contributor.authorTaggart, John Ben_UK
dc.contributor.authorCreer, Simonen_UK
dc.contributor.authorCarvalho, Garyen_UK
dc.contributor.authorOliveira, Claudioen_UK
dc.contributor.authorTaylor, Martin Ien_UK
dc.description.abstractGenome size varies significantly across eukaryotic taxa and the largest changes are typically driven by macro-mutations such as whole genome duplications (WGDs) and proliferation of repetitive elements. These two processes may affect the evolutionary potential of lineages by increasing genetic variation and changing gene expression. Here, we elucidate the evolutionary history and mechanisms underpinning genome size variation in a species-rich group of Neotropical catfishes (Corydoradinae) with extreme variation in genome size—0.6 to 4.4 pg per haploid cell. First, genome size was quantified in 65 species and mapped onto a novel fossil-calibrated phylogeny. Two evolutionary shifts in genome size were identified across the tree—the first between 43 and 49 Ma (95% highest posterior density (HPD) 36.2–68.1 Ma) and the second at approximately 19 Ma (95% HPD 15.3–30.14 Ma). Second, restriction-site-associated DNA (RAD) sequencing was used to identify potential WGD events and quantify transposable element (TE) abundance in different lineages. Evidence of two lineage-scale WGDs was identified across the phylogeny, the first event occurring between 54 and 66 Ma (95% HPD 42.56–99.5 Ma) and the second at 20–30 Ma (95% HPD 15.3–45 Ma) based on haplotype numbers per contig and between 35 and 44 Ma (95% HPD 30.29–64.51 Ma) and 20–30 Ma (95% HPD 15.3–45 Ma) based on SNP read ratios. TE abundance increased considerably in parallel with genome size, with a single TE-family (TC1-IS630-Pogo) showing several increases across the Corydoradinae, with the most recent at 20–30 Ma (95% HPD 15.3–45 Ma) and an older event at 35–44 Ma (95% HPD 30.29–64.51 Ma). We identified signals congruent with two WGD duplication events, as well as an increase in TE abundance across different lineages, making the Corydoradinae an excellent model system to study the effects of WGD and TEs on genome and organismal evolution.en_UK
dc.publisherRoyal Societyen_UK
dc.relationMarburger S, Alexandrou MA, Taggart JB, Creer S, Carvalho G, Oliveira C & Taylor MI (2018) Whole genome duplication and transposable element proliferation drive genome expansion in Corydoradinae catfishes, Proceedings of the Royal Society B: Biological Sciences, 285 (1872), Art. No.: 20172732.
dc.rights© 2018 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License, which permits unrestricted use, provided the original author and source are credited.en_UK
dc.subjectgenome size evolutionen_UK
dc.subjecttransposable elementsen_UK
dc.titleWhole genome duplication and transposable element proliferation drive genome expansion in Corydoradinae catfishesen_UK
dc.typeJournal Articleen_UK
dc.citation.jtitleProceedings of the Royal Society B: Biological Sciencesen_UK
dc.type.statusVoR - Version of Recorden_UK
dc.contributor.funderNatural Environment Research Councilen_UK
dc.contributor.affiliationUniversity of East Angliaen_UK
dc.contributor.affiliationBangor Universityen_UK
dc.contributor.affiliationInstitute of Aquacultureen_UK
dc.contributor.affiliationBangor Universityen_UK
dc.contributor.affiliationBangor Universityen_UK
dc.contributor.affiliationSao Paulo State University (Universidade Estadual Paulista)en_UK
dc.contributor.affiliationUniversity of East Angliaen_UK
dc.description.refREF Compliant by Deposit in Stirling's Repositoryen_UK
Appears in Collections:Aquaculture Journal Articles

Files in This Item:
File Description SizeFormat 
Whole genome duplication and transposable element proliferation.pdfFulltext - Published Version682.59 kBAdobe PDFView/Open

This item is protected by original copyright

Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.

If you believe that any material held in STORRE infringes copyright, please contact providing details and we will remove the Work from public display in STORRE and investigate your claim.