|Appears in Collections:||Psychology Journal Articles|
|Peer Review Status:||Refereed|
|Title:||The chronic and evolving neurological consequences of traumatic brain injury|
|Author(s):||Wilson, J T Lindsay|
Menon, David K
|Citation:||Wilson JTL, Stewart W, Dams-O'Connor K, Diaz-Arrastia R, Horton L, Menon DK & Polinder S (2017) The chronic and evolving neurological consequences of traumatic brain injury, Lancet Neurology, 16 (10), pp. 813-825.|
|Abstract:||Traumatic brain injury (TBI) can have lifelong and dynamic effects on health and wellbeing. Research on the long-term consequences emphasises that, for many patients, TBI should be conceptualised as a chronic health condition. Evidence suggests that functional outcomes after TBI can show improvement or deterioration up to two decades after injury, and rates of all-cause mortality remain elevated for many years. Furthermore, TBI represents a risk factor for a variety of neurological illnesses, including epilepsy, stroke, and neurodegenerative disease. With respect to neurodegeneration after TBI, post-mortem studies on the long-term neuropathology after injury have identified complex persisting and evolving abnormalities best described as polypathology, which includes chronic traumatic encephalopathy. Despite growing awareness of the lifelong consequences of TBI, substantial gaps in research exist. Improvements are therefore needed in understanding chronic pathologies and their implications for survivors of TBI, which could inform long-term health management in this sizeable patient population. This is the fourth in aSeriesof four papers about traumatic brain injury|
|Rights:||This item has been embargoed for a period. During the embargo please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study. Accepted refereed manuscript of: Wilson JTL, Stewart W, Dams-O'Connor K, Diaz-Arrastia R, Horton L, Menon DK & Polinder S (2017) The chronic and evolving neurological consequences of traumatic brain injury, The Lancet Neurology, 16 (10), pp. 813-825. DOI: 10.1016/S1474-4422(17)30279-X © 2017, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/|
|Wilson_etal_LancetNeurology_2017.pdf||1.29 MB||Adobe PDF||View/Open|
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