Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/24104
Full metadata record
DC FieldValueLanguage
dc.contributor.authorWehner, Stefanie-
dc.contributor.authorDamm, Katrin-
dc.contributor.authorHartmann, Roland K-
dc.contributor.authorMarz, Manja-
dc.date.accessioned2016-11-22T22:24:15Z-
dc.date.issued2014-
dc.identifier.urihttp://hdl.handle.net/1893/24104-
dc.description.abstract6S RNA is a highly abundant small non-coding RNA widely spread among diverse bacterial groups. By competing with DNA promoters for binding to RNA polymerase (RNAP), the RNA regulates transcription on a global scale. RNAP produces small product RNAs derived from 6S RNA as template, which rearranges the 6S RNA structure leading to dissociation of 6S RNA:RNAP complexes. Although 6S RNA has been experimentally analysed in detail for some species, such asEscherichia coliandBacillus subtilis, and was computationally predicted in many diverse bacteria, a complete and up-to-date overview of the distribution among all bacteria is missing. In this study we searched with new methods for 6S RNA genes in all currently available bacterial genomes. We ended up with a set of 1,750 6S RNA genes, of which 1,367 are novel and bona fide, distributed among 1,610 bacteria, and had a few tentative candidates among the remaining 510 assembled bacterial genomes accessible. We were able to confirm two tentative candidates by Northern blot analysis. We extended 6S RNA genes of theFlavobacteriiasignificantly in length compared to the presentRfamentry. We describe multiple homologs of 6S RNAs (including split 6S RNA genes) and performed a detailed synteny analysis.en_UK
dc.language.isoen-
dc.publisherTaylor and Francis-
dc.relationWehner S, Damm K, Hartmann RK & Marz M (2014) Dissemination of 6S RNA among bacteria, RNA Biology, 11 (11), pp. 1467-1478.-
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.-
dc.subject6S RNAen_UK
dc.subjectnon-coding RNAen_UK
dc.subjectRNA polymeraseen_UK
dc.subjectregulation of transcriptionen_UK
dc.subjectsecondary structureen_UK
dc.titleDissemination of 6S RNA among bacteriaen_UK
dc.typeJournal Articleen_UK
dc.rights.embargodate2999-12-31T00:00:00Z-
dc.rights.embargoreasonThe publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.-
dc.identifier.doihttp://dx.doi.org/10.4161/rna.29894-
dc.identifier.pmid25483037-
dc.citation.jtitleRNA Biology-
dc.citation.issn1547-6286-
dc.citation.volume11-
dc.citation.issue11-
dc.citation.spage1467-
dc.citation.epage1478-
dc.citation.publicationstatusPublished-
dc.citation.peerreviewedRefereed-
dc.type.statusPublisher version (final published refereed version)-
dc.author.emailstefanie.wehner@stir.ac.uk-
dc.citation.date31/10/2014-
dc.contributor.affiliationAquaculture-
dc.contributor.affiliationPhilipps University of Marburg-
dc.contributor.affiliationPhilipps University of Marburg-
dc.contributor.affiliationPhilipps University of Marburg-
dc.rights.embargoterms2999-12-31-
dc.rights.embargoliftdate2999-12-31-
dc.identifier.isi000350024000015-
Appears in Collections:Aquaculture Journal Articles

Files in This Item:
File Description SizeFormat 
Dissemination of 6S RNA among Bacteria.pdf1.16 MBAdobe PDFUnder Permanent Embargo    Request a copy


This item is protected by original copyright



Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.

If you believe that any material held in STORRE infringes copyright, please contact library@stir.ac.uk providing details and we will remove the Work from public display in STORRE and investigate your claim.