|Appears in Collections:||Aquaculture Journal Articles|
|Peer Review Status:||Refereed|
|Title:||Effect of the arachidonic acid/vitamin E interaction on the immune response of juvenile Atlantic salmon (Salmo salar) challenged against Piscirickettsia salmonis|
|Citation:||Dantagnan P, Gonzalez K, Hevia M, Betancor M, Hernández A, Borquez A & Montero D (2017) Effect of the arachidonic acid/vitamin E interaction on the immune response of juvenile Atlantic salmon (Salmo salar) challenged against Piscirickettsia salmonis. Aquaculture Nutrition, 23 (4), pp. 710-720. https://doi.org/10.1111/anu.12438|
|Abstract:||Atlantic salmon (Salmo salar) were fed 6 experimental dietscontaining three levels of arachidonic acid (ARA) (0.18 g kg−1, 0.28 g kg−1 and 0.63 g kg−1 for low, medium and high levels, respectively) and two levels of vitamin E (150 and 730mg kg−1 for low and high levels, respectively). At the end of the experimental period, fatty acids in the liver and immunity markers (lysozyme activity, respiratory burst and phagocytic activity) were determined and fish subjected to a challenge test against the salmonid rickettsial syndrome (SRS) pathogen. ARA, vitamin E or their interaction did not exert an effect on fish performance, whereas ARA alone clearly increased the deposition of ARA. Dietary vitamin E only enhanced liver vitamin E deposition, while the interaction of ARA and vitamin E influenced lysozyme activity and EPA/ARA ratio pointing out the effect of both nutrients on the fish immune system and metabolism. Only the medium concentration contributed to reducing mortality when the fish were exposed to the SRS pathogen. In conclusion, different levels of supplementation with ARA and vitamin E in the diet had no effect on productivity, but did have effects on immune markers and cumulative mortality when fish were exposed to the SRS pathogen.|
|Rights:||This item has been embargoed for a period. During the embargo please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study. This is the peer reviewed version of the following article: Dantagnan, P., Gonzalez, K., Hevia, M., Betancor, M.B., Hernández, A.J., Borquez, A. and Montero, D. (2017), Effect of the arachidonic acid/vitamin E interaction on the immune response of juvenile Atlantic salmon (Salmo salar) challenged against Piscirickettsia salmonis. Aquacult Nutr, 23: 710–720, which has been published in final form at https://doi.org/10.1111/anu.12438. This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.|
|Dantagnan at al 2016.pdf||Fulltext - Accepted Version||548.36 kB||Adobe PDF||View/Open|
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