Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/22902
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dc.contributor.authorBolund, Elisabeth-
dc.contributor.authorHayward, Adam-
dc.contributor.authorPettay, Jenni E-
dc.contributor.authorLummaa, Virpi-
dc.date.accessioned2016-03-04T23:44:53Z-
dc.date.issued2015-03-
dc.identifier.urihttp://hdl.handle.net/1893/22902-
dc.description.abstractThe recent demographic transitions to lower mortality and fertility rates in most human societies have led to changes and even quick reversals in phenotypic selection pressures. This can only result in evolutionary change if the affected traits are heritable, but changes in environmental conditions may also lead to subsequent changes in the genetic variance and covariance (theGmatrix) of traits. It currently remains unclear if there have been concomitant changes in theGmatrix of life-history traits following the demographic transition. Using 300 years of genealogical data from Finland, we found that four key life-history traits were heritable both before and after the demographic transition. The estimated heritabilities allow a quantifiable genetic response to selection during both time periods, thus facilitating continued evolutionary change. Further, theGmatrices remained largely stable but revealed a trend for an increased additive genetic variance and thus evolutionary potential of the population after the transition. Our results demonstrate the validity of predictions of evolutionary change in human populations even after the recent dramatic environmental change, and facilitate predictions of how our biology interacts with changing environments, with implications for global public health and demography.en_UK
dc.language.isoen-
dc.publisherWiley-Blackwell-
dc.relationBolund E, Hayward A, Pettay JE & Lummaa V (2015) Effects of the demographic transition on the genetic variances and covariances of human life history traits, Evolution, 69 (3), pp. 747-755.-
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.-
dc.subjectGenetic correlationen_UK
dc.subjectheritabilityen_UK
dc.subjectstability of Gen_UK
dc.subjectvariance–covariance matrixen_UK
dc.titleEffects of the demographic transition on the genetic variances and covariances of human life history traitsen_UK
dc.typeJournal Articleen_UK
dc.rights.embargodate2999-12-31T00:00:00Z-
dc.rights.embargoreasonThe publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.-
dc.identifier.doihttp://dx.doi.org/10.1111/evo.12598-
dc.identifier.pmid25564932-
dc.citation.jtitleEvolution-
dc.citation.issn0014-3820-
dc.citation.volume69-
dc.citation.issue3-
dc.citation.spage747-
dc.citation.epage755-
dc.citation.publicationstatusPublished-
dc.citation.peerreviewedRefereed-
dc.type.statusPublisher version (final published refereed version)-
dc.author.emailadam.hayward@stir.ac.uk-
dc.citation.date07/01/2015-
dc.contributor.affiliationUniversity of Sheffield-
dc.contributor.affiliationBiological and Environmental Sciences-
dc.contributor.affiliationUniversity of Turku-
dc.contributor.affiliationUniversity of Sheffield-
dc.rights.embargoterms2999-12-31-
dc.rights.embargoliftdate2999-12-31-
dc.identifier.isi000351446000015-
Appears in Collections:Biological and Environmental Sciences Journal Articles

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