Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/22266
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dc.contributor.authorLi, Shu-Chen-
dc.contributor.authorBrehmer, Yvonne-
dc.contributor.authorShing, Yee Lee-
dc.contributor.authorWerkle-Bergner, Markus-
dc.contributor.authorLindenberger, Ulman-
dc.date.accessioned2015-09-30T00:01:12Z-
dc.date.issued2006-
dc.identifier.urihttp://hdl.handle.net/1893/22266-
dc.description.abstractDevelopmental plasticity is the key mechanism that allows humans and other organisms to modify and adapt to contextual and experiential influences. Thus, reciprocal co-constructive interactions between behavioral and neuronal plasticity play important roles in regulating neurobehavioral development across the life span. This review focuses on behavioral and neuronal evidence of lifespan differences in associative memory plasticity and plasticity of the functional organization of cognitive and cortical processes, as well as the role of the dopaminergic system in modulating such plasticity. Special attention is given to neurocomputational models that help exploring lifespan differences in neuromodulation of neuronal and behavioral plasticity. Simulation results from these models suggest that lifespan changes in the efficacy of neuromodulatory mechanisms may shape associative memory plasticity and the functional organization of neurocognitive processes by affecting the fidelity of neuronal signal transmission, which has consequences for the distinctiveness of neurocognitive representations and the efficacy of distributed neural coding.en_UK
dc.language.isoen-
dc.publisherElsevier-
dc.relationLi S, Brehmer Y, Shing YL, Werkle-Bergner M & Lindenberger U (2006) Neuromodulation of associative and organizational plasticity across the life span: Empirical evidence and neurocomputational modeling, Neuroscience and Biobehavioral Reviews, 30 (6), pp. 775-790.-
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.-
dc.subjectNeural plasticityen_UK
dc.subjectMemory plasticityen_UK
dc.subjectNeuromodulationen_UK
dc.subjectNeural networksen_UK
dc.subjectSignal-to-noiseen_UK
dc.subjectNeuroconstructivismen_UK
dc.titleNeuromodulation of associative and organizational plasticity across the life span: Empirical evidence and neurocomputational modelingen_UK
dc.typeJournal Articleen_UK
dc.rights.embargodate2999-12-31T00:00:00Z-
dc.rights.embargoreasonThe publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.-
dc.identifier.doihttp://dx.doi.org/10.1016/j.neubiorev.2006.06.004-
dc.identifier.pmid16930705-
dc.citation.jtitleNeuroscience and Biobehavioral Reviews-
dc.citation.issn0149-7634-
dc.citation.volume30-
dc.citation.issue6-
dc.citation.spage775-
dc.citation.epage790-
dc.citation.publicationstatusPublished-
dc.citation.peerreviewedRefereed-
dc.type.statusPublisher version (final published refereed version)-
dc.author.emailyee.shing@stir.ac.uk-
dc.contributor.affiliationMax Planck Institute for Human Development-
dc.contributor.affiliationMax Planck Institute for Human Development-
dc.contributor.affiliationPsychology-
dc.contributor.affiliationMax Planck Institute for Human Development-
dc.contributor.affiliationMax Planck Institute for Human Development-
dc.rights.embargoterms2999-12-31-
dc.rights.embargoliftdate2999-12-31-
dc.identifier.isi000241208800006-
Appears in Collections:Psychology Journal Articles

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