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Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/22255
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dc.contributor.authorRoy, Priti Kumaren_UK
dc.contributor.authorChowdhury, Soniaen_UK
dc.contributor.authorChatterjee, Amar Nathen_UK
dc.contributor.authorChattopadhyay, Joydeven_UK
dc.contributor.authorNorman, Rachelen_UK
dc.date.accessioned2015-09-29T23:18:22Z-
dc.date.available2015-09-29T23:18:22Z-
dc.date.issued2013-09en_UK
dc.identifier.other1350019en_UK
dc.identifier.urihttp://hdl.handle.net/1893/22255-
dc.description.abstractBonhoeffer et al.1 studied the long-term dynamics of HIV drug therapy and virus load dynamics. It is well known that highly active anti retroviral therapy (HAART) can effectively control the HIV replication. It is also well known that reverse transcriptase inhibitors (RTIs) could block new infection and as a result control HIV infection. The positive feedback control on such dynamics plays an important role and CD4+T cells are not only produced from a source but also produced from existing T cells. The present investigation takes into account these factors in the original model of Bonhoeffer et al. The optimal control therapy and the effect of time delay in the positive feedback control function have been investigated. Numerical simulation of the nonlinear model has confirmed our analytical studies.Read More: http://www.worldscientific.com/doi/abs/10.1142/S0218339013500198en_UK
dc.language.isoenen_UK
dc.publisherWorld Scientificen_UK
dc.relationRoy PK, Chowdhury S, Chatterjee AN, Chattopadhyay J & Norman R (2013) A mathematical model on CTL mediated control of hiv infection in a long-term drug therapy. Journal of Biological Systems, 21 (3), Art. No.: 1350019. https://doi.org/10.1142/S0218339013500198en_UK
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.en_UK
dc.rights.urihttp://www.rioxx.net/licenses/under-embargo-all-rights-reserveden_UK
dc.subjectFeedback Controlen_UK
dc.subjectAsymptotic Stabilityen_UK
dc.subjectCD4+T Cellsen_UK
dc.subjectCTLen_UK
dc.subjectHAARTen_UK
dc.subjectHIVen_UK
dc.subjectT Cell Proliferationen_UK
dc.subjectOptimal Controlen_UK
dc.subjectDelayen_UK
dc.titleA mathematical model on CTL mediated control of hiv infection in a long-term drug therapyen_UK
dc.typeJournal Articleen_UK
dc.rights.embargodate2999-12-31en_UK
dc.rights.embargoreason[Roy et al_JBS_2013.pdf] The publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.en_UK
dc.identifier.doi10.1142/S0218339013500198en_UK
dc.citation.jtitleJournal of Biological Systemsen_UK
dc.citation.issn1793-6470en_UK
dc.citation.issn0218-3390en_UK
dc.citation.volume21en_UK
dc.citation.issue3en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedRefereeden_UK
dc.type.statusVoR - Version of Recorden_UK
dc.author.emailr.a.norman@stir.ac.uken_UK
dc.contributor.affiliationJadavpur Universityen_UK
dc.contributor.affiliationJadavpur Universityen_UK
dc.contributor.affiliationJadavpur Universityen_UK
dc.contributor.affiliationIndian Statistical Instituteen_UK
dc.contributor.affiliationComplex Systems - LEGACYen_UK
dc.identifier.isiWOS:000324744900004en_UK
dc.identifier.scopusid2-s2.0-84884559325en_UK
dc.identifier.wtid660776en_UK
dc.contributor.orcid0000-0002-7398-6064en_UK
dc.date.accepted2013-04-18en_UK
dcterms.dateAccepted2013-04-18en_UK
dc.date.filedepositdate2015-09-29en_UK
rioxxterms.typeJournal Article/Reviewen_UK
rioxxterms.versionVoRen_UK
local.rioxx.authorRoy, Priti Kumar|en_UK
local.rioxx.authorChowdhury, Sonia|en_UK
local.rioxx.authorChatterjee, Amar Nath|en_UK
local.rioxx.authorChattopadhyay, Joydev|en_UK
local.rioxx.authorNorman, Rachel|0000-0002-7398-6064en_UK
local.rioxx.projectInternal Project|University of Stirling|https://isni.org/isni/0000000122484331en_UK
local.rioxx.freetoreaddate2999-12-31en_UK
local.rioxx.licencehttp://www.rioxx.net/licenses/under-embargo-all-rights-reserved||en_UK
local.rioxx.filenameRoy et al_JBS_2013.pdfen_UK
local.rioxx.filecount1en_UK
local.rioxx.source0218-3390en_UK
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