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dc.contributor.authorAnderson, Annie Sen_UK
dc.contributor.authorMacleod, Maureenen_UK
dc.contributor.authorMutrie, Nanetteen_UK
dc.contributor.authorSugden, Jacquelineen_UK
dc.contributor.authorDobson, Hilaryen_UK
dc.contributor.authorTreweek, Shaunen_UK
dc.contributor.authorO'Carroll, Ronanen_UK
dc.contributor.authorThompson, Alastair Men_UK
dc.contributor.authorKirk, Alisonen_UK
dc.contributor.authorBrennan, Grahamen_UK
dc.contributor.authorWyke, Sallyen_UK
dc.description.abstractBackground: Breast cancer is the most commonly diagnosed cancer and the second cause of cancer deaths amongst women in the UK. The incidence of the disease is increasing and is highest in women from least deprived areas. It is estimated that around 42% of the disease in post-menopausal women could be prevented by increased physical activity and reductions in alcohol intake and body fatness. Breast cancer control endeavours focus on national screening programmes but these do not include communications or interventions for risk reduction. This study aimed to assess the feasibility of delivery, indicative effects and acceptability of a lifestyle intervention programme initiated within the NHS Scottish Breast Screening Programme (NHSSBSP). Methods: A 1:1 randomised controlled trial (RCT) of the 3month ActWell programme (focussing on body weight, physical activity and alcohol) versus usual care conducted in two NHSSBSP sites between June 2013 and January 2014. Feasibility assessments included recruitment, retention, and fidelity to protocol. Indicative outcomes were measured at baseline and 3month follow-up (body weight, waist circumference, eating and alcohol habits and physical activity). At study end, a questionnaire assessed participant satisfaction and qualitative interviews elicited women's, coaches, and radiographers' experiences. Statistical analysis used Chi squared tests for comparisons in proportions and paired t tests for comparisons of means. Linear regression analyses were performed, adjusted for baseline values, with group allocation as a fixed effect. Results: A pre-set recruitment target of 80 women was achieved within 12weeks and 65 (81%) participants (29 intervention, 36 control) completed 3month assessments. Mean age was 58 ± 5.6years, mean BMI was 29.2 ± 7.0kg/m2 and many (44%) reported a family history of breast cancer. The primary analysis (baseline body weight adjusted) showed a significant between group difference favouring the intervention group of 2.04kg (95% CI -3.24kg to -0.85kg). Significant, favourable between group differences were also detected for BMI, waist circumference, physical activity and sitting time. Women rated the programme highly and 70% said they would recommend it to others. Conclusions: Recruitment, retention, indicative results and participant acceptability support the development of a definitive RCT to measure long term effects. Trial registration: The trial was registered with Current Controlled Trials (ISRCTN56223933)en_UK
dc.publisherBioMed Centralen_UK
dc.relationAnderson AS, Macleod M, Mutrie N, Sugden J, Dobson H, Treweek S, O'Carroll R, Thompson AM, Kirk A, Brennan G & Wyke S (2014) Breast cancer risk reduction - is it feasible to initiate a randomised controlled trial of a lifestyle intervention programme (ActWell) within a national breast screening programme?. International Journal of Behavioral Nutrition and Physical Activity, 11 (1), Art. No.: 156.
dc.rights© 2014 Anderson et al.; licensee BioMed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.en_UK
dc.subjectBreast canceren_UK
dc.subjectPhysical activityen_UK
dc.subjectBody weighten_UK
dc.subjectSedentary timeen_UK
dc.titleBreast cancer risk reduction - is it feasible to initiate a randomised controlled trial of a lifestyle intervention programme (ActWell) within a national breast screening programme?en_UK
dc.typeJournal Articleen_UK
dc.citation.jtitleInternational Journal of Behavioral Nutrition and Physical Activityen_UK
dc.type.statusVoR - Version of Recorden_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationUniversity of Edinburghen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationNHS National Services Scotlanden_UK
dc.contributor.affiliationUniversity of Aberdeenen_UK
dc.contributor.affiliationUniversity of Dundeeen_UK
dc.contributor.affiliationUniversity of Strathclydeen_UK
dc.contributor.affiliationUniversity of Glasgowen_UK
dc.contributor.affiliationUniversity of Glasgowen_UK
rioxxterms.apcnot requireden_UK
rioxxterms.typeJournal Article/Reviewen_UK
local.rioxx.authorAnderson, Annie S|en_UK
local.rioxx.authorMacleod, Maureen|en_UK
local.rioxx.authorMutrie, Nanette|en_UK
local.rioxx.authorSugden, Jacqueline|en_UK
local.rioxx.authorDobson, Hilary|en_UK
local.rioxx.authorTreweek, Shaun|en_UK
local.rioxx.authorO'Carroll, Ronan|0000-0002-5130-291Xen_UK
local.rioxx.authorThompson, Alastair M|en_UK
local.rioxx.authorKirk, Alison|en_UK
local.rioxx.authorBrennan, Graham|en_UK
local.rioxx.authorWyke, Sally|en_UK
local.rioxx.projectInternal Project|University of Stirling|
Appears in Collections:Psychology Journal Articles

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