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dc.contributor.authorWeidmann, Manfreden_UK
dc.contributor.authorRuzek, Danielen_UK
dc.contributor.authorKrivanec, Karelen_UK
dc.contributor.authorZoller, Gudrunen_UK
dc.contributor.authorEssbauer, Sandraen_UK
dc.contributor.authorPfeffer, Martinen_UK
dc.contributor.authorZanotto, Paolo M D Aen_UK
dc.contributor.authorHufert, Frank Ten_UK
dc.contributor.authorDobler, Gerharden_UK
dc.description.abstractTick-borne encephalitis virus (TBEV) is the most important arboviral agent causing disease of the central nervous system in central Europe. In this study, 61 TBEV E gene sequences derived from 48 isolates from the Czech Republic, and four isolates and nine TBEV strains detected in ticks from Germany, covering more than half a century from 1954 to 2009, were sequenced and subjected to phylogenetic and Bayesian phylodynamic analysis to determine the phylogeography of TBEV in central Europe. The general Eurasian continental east-to-west pattern of the spread of TBEV was confirmed at the regional level but is interlaced with spreading that arises because of local geography and anthropogenic influence. This spread is reflected by the disease pattern in the Czech Republic that has been observed since 1991. The overall evolutionary rate was estimated to be approximately 8×10-4 substitutions per nucleotide per year. The analysis of the TBEV E genes of 11 strains isolated at one natural focus in Žďár Kaplice proved for the first time that TBEV is indeed subject to local evolution.en_UK
dc.publisherSociety for General Microbiologyen_UK
dc.relationWeidmann M, Ruzek D, Krivanec K, Zoller G, Essbauer S, Pfeffer M, Zanotto PMDA, Hufert FT & Dobler G (2011) Relation of genetic phylogeny and geographical distance of tick-borne encephalitis virus in central Europe. Journal of General Virology, 92 (8), pp. 1906-1916.
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.en_UK
dc.titleRelation of genetic phylogeny and geographical distance of tick-borne encephalitis virus in central Europeen_UK
dc.typeJournal Articleen_UK
dc.rights.embargoreason[JGV 2011.pdf] The publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.en_UK
dc.citation.jtitleJournal of General Virologyen_UK
dc.type.statusVoR - Version of Recorden_UK
dc.contributor.affiliationInstitute of Aquacultureen_UK
dc.contributor.affiliationCzech Academy of Sciencesen_UK
dc.contributor.affiliationMinistry of Defence & Armed Forces of the Czech Republicen_UK
dc.contributor.affiliationBunderwehr Institute for Microbiologyen_UK
dc.contributor.affiliationBunderwehr Institute for Microbiologyen_UK
dc.contributor.affiliationUniversity Leipzigen_UK
dc.contributor.affiliationUniversity of Sao Pauloen_UK
dc.contributor.affiliationGeorg-August University Gottingenen_UK
dc.contributor.affiliationBunderwehr Institute for Microbiologyen_UK
rioxxterms.typeJournal Article/Reviewen_UK
local.rioxx.authorWeidmann, Manfred|0000-0002-7063-7491en_UK
local.rioxx.authorRuzek, Daniel|en_UK
local.rioxx.authorKrivanec, Karel|en_UK
local.rioxx.authorZoller, Gudrun|en_UK
local.rioxx.authorEssbauer, Sandra|en_UK
local.rioxx.authorPfeffer, Martin|en_UK
local.rioxx.authorZanotto, Paolo M D A|en_UK
local.rioxx.authorHufert, Frank T|en_UK
local.rioxx.authorDobler, Gerhard|en_UK
local.rioxx.projectInternal Project|University of Stirling|
local.rioxx.filenameJGV 2011.pdfen_UK
Appears in Collections:Aquaculture Journal Articles

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