Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/18255
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dc.contributor.authorDilcher, Meik-
dc.contributor.authorKoch, Andrea-
dc.contributor.authorHasib, Lekbira-
dc.contributor.authorDobler, Gerhard-
dc.contributor.authorHufert, Frank T-
dc.contributor.authorWeidmann, Manfred-
dc.date.accessioned2015-07-23T03:28:09Z-
dc.date.available2015-07-23T03:28:09Z-
dc.date.issued2012-12-
dc.identifier.urihttp://hdl.handle.net/1893/18255-
dc.description.abstractErve virus (ERVEV) is a European Nairovirus that is suspected to cause severe headache (thunderclap headache) and intracerebral hemorrhage. The mode of transmission to humans (ticks or mosquitoes) is still unknown. Currently, no standardized testing method for ERVEV exists and only a small partial sequence of the polymerase gene is available. Here, we present the first complete genome sequence of ERVEV S, M, and L segments. Phylogenetic comparison of the amino acid sequence of the L-protein (RNA-dependent RNA polymerase) revealed only 48 % homology to available L-protein sequences of other Nairoviruses like Crimean-Congo hemorrhagic fever virus, Nairobi sheep disease virus, Hazara virus, Kupe virus, and Dugbe virus. Among themselves, these Nairoviruses show 62-89 % homology in the L-protein sequences. Therefore, ERVEV seems to be only distantly related to other Nairoviruses. The new sequence data can be used for the development of diagnostic methods and the identification of the natural vector.en_UK
dc.language.isoen-
dc.publisherSpringer-
dc.relationDilcher M, Koch A, Hasib L, Dobler G, Hufert FT & Weidmann M (2012) Genetic characterization of Erve virus, a European Nairovirus distantly related to Crimean-Congo hemorrhagic fever virus, Virus Genes, 45 (3), pp. 426-432.-
dc.rightsCopyright is held by The Author(s) 2012. This article is published with open access at Springerlink.com-
dc.subjectErve virusen_UK
dc.subjectBunyavirusen_UK
dc.subjectNairovirusen_UK
dc.subjectThiafora groupen_UK
dc.titleGenetic characterization of Erve virus, a European Nairovirus distantly related to Crimean-Congo hemorrhagic fever virusen_UK
dc.typeJournal Articleen_UK
dc.identifier.doihttp://dx.doi.org/10.1007/s11262-012-0796-8-
dc.citation.jtitleVirus Genes-
dc.citation.issn0920-8569-
dc.citation.volume45-
dc.citation.issue3-
dc.citation.spage426-
dc.citation.epage432-
dc.citation.publicationstatusPublished-
dc.citation.peerreviewedRefereed-
dc.type.statusPublisher version (final published refereed version)-
dc.author.emailm.w.weidmann@stir.ac.uk-
dc.contributor.affiliationUniversity of Gottingen, Georg-August University-
dc.contributor.affiliationUniversity of Gottingen, Georg-August University-
dc.contributor.affiliationUniversity of Gottingen, Georg-August University-
dc.contributor.affiliationBunderwehr Institute for Microbiology-
dc.contributor.affiliationUniversity of Gottingen, Georg-August University-
dc.contributor.affiliationAquaculture-
dc.identifier.isi000312532600002-
Appears in Collections:Aquaculture Journal Articles

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