Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/17951
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dc.contributor.authorDudchenko, Paul-
dc.contributor.authorTalpos, John-
dc.contributor.authorYoung, Jared-
dc.contributor.authorBaxter, Mark G-
dc.date.accessioned2018-01-27T02:56:08Z-
dc.date.issued2013-11-
dc.identifier.urihttp://hdl.handle.net/1893/17951-
dc.description.abstractThe Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) meeting on "Selecting Promising Animal Paradigms" focused on a consideration of valid tasks for drug discovery in non-humans. This review is based on a break-out session with experts from academia and industry which considered tasks that tap working memory in animals. The specific focus of session was on tasks measuring goal maintenance, memory capacity, and interference control. Of the tasks nominated for goal maintenance, the most developed paradigms were operant delayed-non-matching-to-position tasks, and touch-screen variants of these may hold particular promise. For memory capacity, the task recommended for further development was the span task, although it is recognized that more work on its neural substrates is required. For interference control, versions of the n-back task were felt to resemble the deficits found in schizophrenia, although additional development of these tasks is also required.en_UK
dc.language.isoen-
dc.publisherElsevier-
dc.relationDudchenko P, Talpos J, Young J & Baxter MG (2013) Animal models of working memory: a review of tasks that might be used in screening drug treatments for the memory impairments found in schizophrenia, Neuroscience and Biobehavioral Reviews, 37 (9, Part B), pp. 2111-2124.-
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.-
dc.subjectWorking memoryen_UK
dc.subjectDelayed non-matching to positionen_UK
dc.subjectOdour spanen_UK
dc.subjectn-Backen_UK
dc.subjectSchizophreniaen_UK
dc.subjectAnimal modelsen_UK
dc.titleAnimal models of working memory: a review of tasks that might be used in screening drug treatments for the memory impairments found in schizophreniaen_UK
dc.typeJournal Articleen_UK
dc.rights.embargodate2999-12-31T00:00:00Z-
dc.rights.embargoreasonThe publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.-
dc.identifier.doihttp://dx.doi.org/10.1016/j.neubiorev.2012.03.003-
dc.citation.jtitleNeuroscience and Biobehavioral Reviews-
dc.citation.issn0149-7634-
dc.citation.volume37-
dc.citation.issue9, Part B-
dc.citation.spage2111-
dc.citation.epage2124-
dc.citation.publicationstatusPublished-
dc.citation.peerreviewedRefereed-
dc.type.statusPublisher version (final published refereed version)-
dc.author.emailp.a.dudchenko@stir.ac.uk-
dc.citation.date22/03/2012-
dc.contributor.affiliationPsychology-
dc.contributor.affiliationJohnson & Johnson-
dc.contributor.affiliationUniversity of California-
dc.contributor.affiliationMount Sinai School of Medicine-
dc.rights.embargoterms2999-12-31-
dc.rights.embargoliftdate2999-12-31-
dc.identifier.isi000329884000004-
Appears in Collections:Psychology Journal Articles

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