Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/15457
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dc.contributor.authorPoobalane, Saravananeen_UK
dc.contributor.authorThompson, Kimberlyen_UK
dc.contributor.authorArdo, Laszloen_UK
dc.contributor.authorVerjan, Noelen_UK
dc.contributor.authorHan, Hyun-Jaen_UK
dc.contributor.authorJeney, Galinaen_UK
dc.contributor.authorHirono, Ikuoen_UK
dc.contributor.authorAoki, Takashien_UK
dc.contributor.authorAdams, Alexandraen_UK
dc.date.accessioned2018-04-18T02:21:00Z-
dc.date.available2018-04-18T02:21:00Zen_UK
dc.date.issued2010-04en_UK
dc.identifier.urihttp://hdl.handle.net/1893/15457-
dc.description.abstractA recombinant protein for the S-layer protein of Aeromonas hydrophila was produced and its ability to protect common carp Cyprinus carpio L. against six virulent isolates of A. hydrophila was assessed. A group of 120 carp (30-40 g) were vaccinated intra-peritoneally with 0.1 ml of adjuvanted vaccine (30 μg protein per fish). Another group of 120 carp were injected with 0.1 ml of PBS-adjuvant mixture to serve as controls. Twenty fish from each group were challenged with each one of six virulent isolates of A. hydrophila 35 days post-vaccination. The fish were maintained in 12 separate tanks before terminating the experiment at 16 days post-challenge. The relative percentage survival (RPS) for the six isolates of A. hydrophila ranged from 56 to 87%. The difference in survival rate of fish challenged with four of the isolates was statistically significant in vaccinated fish compared to control fish, when analysed using a Chi-square test. The results of the study suggest that the recombinant S-layer protein of A. hydrophila could be useful as a vaccine antigen to protect fish against different isolates of this pathogenic bacterium.en_UK
dc.language.isoenen_UK
dc.publisherElsevieren_UK
dc.relationPoobalane S, Thompson K, Ardo L, Verjan N, Han H, Jeney G, Hirono I, Aoki T & Adams A (2010) Production and efficacy of an Aeromonas hydrophila recombinant S-layer protein vaccine for fish. Vaccine, 28 (20), pp. 3540-3547. https://doi.org/10.1016/j.vaccine.2010.03.011en_UK
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.en_UK
dc.rights.urihttp://www.rioxx.net/licenses/under-embargo-all-rights-reserveden_UK
dc.subjectAeromonas hydrophilaen_UK
dc.subjectRecombinant S-layer protein vaccineen_UK
dc.subjectEfficacy testingen_UK
dc.subjectCommon carpen_UK
dc.subjectAeromonas hydrophilaen_UK
dc.subjectFishes Diseases Vaccinesen_UK
dc.titleProduction and efficacy of an Aeromonas hydrophila recombinant S-layer protein vaccine for fishen_UK
dc.typeJournal Articleen_UK
dc.rights.embargodate2999-12-31en_UK
dc.rights.embargoreason[vaccine 2010.pdf] The publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.en_UK
dc.identifier.doi10.1016/j.vaccine.2010.03.011en_UK
dc.identifier.pmid20307596en_UK
dc.citation.jtitleVaccineen_UK
dc.citation.issn0264-410Xen_UK
dc.citation.volume28en_UK
dc.citation.issue20en_UK
dc.citation.spage3540en_UK
dc.citation.epage3547en_UK
dc.citation.publicationstatusPublisheden_UK
dc.citation.peerreviewedRefereeden_UK
dc.type.statusVoR - Version of Recorden_UK
dc.author.emailalexandra.adams@stir.ac.uken_UK
dc.contributor.affiliationInstitute of Aquacultureen_UK
dc.contributor.affiliationInstitute of Aquacultureen_UK
dc.contributor.affiliationResearch Institute Fisheries, Aquaculture and Irrigationen_UK
dc.contributor.affiliationTokyo University of Marine Science and Technologyen_UK
dc.contributor.affiliationTokyo University of Marine Science and Technologyen_UK
dc.contributor.affiliationResearch Institute Fisheries, Aquaculture and Irrigationen_UK
dc.contributor.affiliationTokyo University of Marine Science and Technologyen_UK
dc.contributor.affiliationTokyo University of Fisheriesen_UK
dc.contributor.affiliationInstitute of Aquacultureen_UK
dc.identifier.isiWOS:000277882600006en_UK
dc.identifier.scopusid2-s2.0-77950631096en_UK
dc.identifier.wtid887811en_UK
dcterms.dateAccepted2010-04-30en_UK
dc.date.filedepositdate2013-06-12en_UK
rioxxterms.typeJournal Article/Reviewen_UK
rioxxterms.versionVoRen_UK
local.rioxx.authorPoobalane, Saravanane|en_UK
local.rioxx.authorThompson, Kimberly|en_UK
local.rioxx.authorArdo, Laszlo|en_UK
local.rioxx.authorVerjan, Noel|en_UK
local.rioxx.authorHan, Hyun-Ja|en_UK
local.rioxx.authorJeney, Galina|en_UK
local.rioxx.authorHirono, Ikuo|en_UK
local.rioxx.authorAoki, Takashi|en_UK
local.rioxx.authorAdams, Alexandra|en_UK
local.rioxx.projectInternal Project|University of Stirling|https://isni.org/isni/0000000122484331en_UK
local.rioxx.freetoreaddate2999-12-31en_UK
local.rioxx.licencehttp://www.rioxx.net/licenses/under-embargo-all-rights-reserved||en_UK
local.rioxx.filenamevaccine 2010.pdfen_UK
local.rioxx.filecount1en_UK
local.rioxx.source0264-410Xen_UK
Appears in Collections:Aquaculture Journal Articles

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