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dc.contributor.authorKwon, Joon Yeong-
dc.contributor.authorMcAndrew, Brendan-
dc.contributor.authorPenman, David-
dc.description.abstractHigh temperature (36° C) treatment during sexual differentiation caused significant changes in sex ratio in YY male Nile tilapia Oreochromis niloticus fry (64.5% males compared to 100.0% males at 28° C), while dietary treatment with a chemical aromatase inhibitor (AI: FadrozoleTM CGS16949A) during this period suppressed the high temperature feminization (98.9% males). This implies that cytochrome P450 aromatase is mechanistically associated with temperature-dependent sex determination (TSD) in this species. XY male fry did not show significant sex reversal at 36° C. In XX female fry, high temperature treatment resulted in significant masculinization (62.5% males compared with 21.9% males at 28° C), while treatment with AI at either temperature resulted in very high proportions of males (100.0% males at 36° C; 99.0% males at 28° C). These results confirm the importance of aromatase in sexual differentiation in the Nile tilapia below the TSD threshold and suggest that it also plays a role in TSD, at least in the YY genotype.en_UK
dc.relationKwon JY, McAndrew B & Penman D (2002) Treatment with an aromatase inhibitor suppresses high-temperature feminization of genetic male (YY) Nile tilapia, Journal of Fish Biology, 60 (3), pp. 625-636.-
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.-
dc.subjectgenetic sex determinationen_UK
dc.subjecttemperature-dependent sex determinationen_UK
dc.subjectsexual differentiationen_UK
dc.subjectOreochromis niloticusen_UK
dc.subject.lcshFishes Sexing-
dc.subject.lcshFishes Genetics-
dc.subject.lcshFishes Sex ratio-
dc.subject.lcshFishes Reproduction-
dc.titleTreatment with an aromatase inhibitor suppresses high-temperature feminization of genetic male (YY) Nile tilapiaen_UK
dc.typeJournal Articleen_UK
dc.rights.embargoreasonThe publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.-
dc.citation.jtitleJournal of Fish Biology-
dc.type.statusPublisher version (final published refereed version)-
dc.contributor.affiliationUniversity of Stirling-
Appears in Collections:Aquaculture Journal Articles

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