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dc.contributor.authorO'Carroll, Ronanen_UK
dc.contributor.authorMasterton, Georgeen_UK
dc.contributor.authorDougall, Nadineen_UK
dc.contributor.authorEbmeier, Klaus Pen_UK
dc.contributor.authorGoodwin, Guy Men_UK
dc.description.abstractBACKGROUND The detailed effects of mercury poisoning on cognitive function, brain anatomy and regional brain function are largely unknown. We report the case of a 38-year-old man who was exposed to toxic levels of inorganic mercury. METHOD Four years after exposure, the patient was assessed using magnetic resonance imaging (MRI), single-photon emission computerised tomography (SPECT) and detailed neuropsychological evaluation. RESULTS The patient developed a myriad of physical and psychiatric complaints, including stomatitis, muscle spasm, tremor, skin rash and the psychiatric syndrome known as 'erythism' (Mad Hatter's disease). Neuropsychological evaluation revealed marked and significant deficits of attention concentration, particularly when under time pressure. The MRI scan was unremarkable; however, SPECT revealed hypermetabolism of the posterior cingulate CONCLUSIONS Mercury poisoning appeared to result in a dysregulation of posterior cingulate cortex, which was associated with attention/concentration deficits and marked anxiety/agitation.en_UK
dc.publisherThe Royal College of Psychiatristsen_UK
dc.relationO'Carroll R, Masterton G, Dougall N, Ebmeier KP & Goodwin GM (1995) The neuropsychiatric sequelae of mercury poisoning. The Mad Hatter's disease revisited, British Journal of Psychiatry, 167 (1), pp. 95-98.
dc.rightsThe publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.en_UK
dc.titleThe neuropsychiatric sequelae of mercury poisoning. The Mad Hatter's disease revisiteden_UK
dc.typeJournal Articleen_UK
dc.rights.embargoreason[O'Carroll et al_BJP_1995.pdf] : The publisher does not allow this work to be made publicly available in this Repository therefore there is an embargo on the full text of the work.en_UK
dc.citation.jtitleBritish Journal of Psychiatryen_UK
dc.type.statusVoR - Version of Recorden_UK
dc.contributor.affiliationRoyal Infirmary of Edinburghen_UK
dc.contributor.affiliationRoyal Edinburgh Hospital (NHS Lothian)en_UK
dc.contributor.affiliationUniversity of Oxforden_UK
Appears in Collections:Psychology Journal Articles

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