Please use this identifier to cite or link to this item:
Appears in Collections:Psychology Journal Articles
Peer Review Status: Refereed
Title: Lessons from traumatic head injury for assessing functional status after brain tumour
Authors: Wilson, J T Lindsay
Contact Email:
Keywords: Brain tumour
Traumatic brain injury
Outcome assessment
Glasgow Outcome Scale
Karnofsky Performance Status
Issue Date: Jun-2012
Publisher: Springer
Citation: Wilson JTL (2012) Lessons from traumatic head injury for assessing functional status after brain tumour, Journal of Neuro-Oncology, 108 (2), pp. 239-246.
Abstract: Assessment of global functional status plays a central role in describing outcome after traumatic head injury, but has played a relatively minor role as an endpoint in brain tumour studies. Advantages of functional status as an outcome include simplicity, objectivity, and interpretability, and it is particularly useful in conditions where cognitive impairment is common. Work in the field of traumatic brain injury, specifically on the Glasgow Outcome Scale (GOS), provides lessons in how the validity and reliability of global outcome assessment can be improved. Functional status is conceptually and empirically distinct from cognition and health-related quality of life, and neither of these can adequately substitute for it as an outcome. The strongest candidate for a global outcome measure in brain tumour work is the Karnofsky Performance Status (KPS). Many of the lessons from the GOS could be applied to improvement of KPS assessment. However, the KPS has additional limitations, particularly that it is not brain injury specific. Global functional status is potentially a useful outcome for brain tumour studies, but there is a gap in the tools currently available.
Type: Journal Article
DOI Link:
Rights: The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.
Affiliation: Psychology

Files in This Item:
File Description SizeFormat 
jtlwilson_JNO_2012.pdf261.78 kBAdobe PDFUnder Embargo until 31/12/2999     Request a copy

Note: If any of the files in this item are currently embargoed, you can request a copy directly from the author by clicking the padlock icon above. However, this facility is dependant on the depositor still being contactable at their original email address.

This item is protected by original copyright

Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.

If you believe that any material held in STORRE infringes copyright, please contact providing details and we will remove the Work from public display in STORRE and investigate your claim.