Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/25807
Appears in Collections:Psychology Journal Articles
Peer Review Status: Refereed
Title: Field repetition and local mapping in the hippocampus and medial entorhinal cortex
Authors: Grieves, Roddy
Duvelle, Eleonore
Wood, Emma R
Dudchenko, Paul
Contact Email: p.a.dudchenko@stir.ac.uk
Keywords: spatial cognition
place cell
grid cell
field repetition
fragmentation
multicompartment
pattern repetition
Issue Date: 1-Oct-2017
Citation: Grieves R, Duvelle E, Wood ER & Dudchenko P (2017) Field repetition and local mapping in the hippocampus and medial entorhinal cortex, Journal of Neurophysiology, 118 (4), pp. 2378-2388.
Abstract: Hippocampal place cells support spatial cognition and are thought to form the neural substrate of a global 'cognitive map'. A widely held view is that parts of the hippocampus also underlie the ability to separate patterns, or to provide different neural codes for distinct environments. However, a number of studies have shown that in environments composed of multiple, repeating compartments, place cells and other spatially modulated neurons show the same activity in each local area. This repetition of firing fields may reflect pattern completion, and may make it difficult for animals to distinguish similar local environments. In this review we will (a) highlight some of the navigation difficulties encountered by humans in repetitive environments, (b) summarise literature demonstrating that place and grid cells represent local and not global space, and (c) attempt to explain the origin of these phenomena. We argue that the repetition of firing fields can be a useful tool for understanding of the relationship between grid cells in the entorhinal cortex and place cells in the hippocampus, the spatial inputs shared by these cells, and the propagation of spatially-related signals through these structures.
DOI Link: http://dx.doi.org/10.1152/jn.00933.2016
Rights: This item has been embargoed for a period. During the embargo please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study. Copyright 2017, American Psychological Society, Journal of Neurophysiology Published 1 October 2017 Vol. 118 no. 4, 2378-2388. The final published version is available at: https://doi.org/10.1152/jn.00933.2016

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