|Appears in Collections:||Aquaculture Journal Articles|
|Peer Review Status:||Refereed|
|Title:||Depletion of emamectin residues following oral administration to rainbow trout, Oncorhynchus mykiss|
Rodger, Hamish D
Endris, Richard G
|Citation:||Roy W, Gillan N, Crouch L, Parker R, Rodger HD & Endris RG (2006) Depletion of emamectin residues following oral administration to rainbow trout, Oncorhynchus mykiss, Aquaculture, 259 (1-4), pp. 6-16.|
|Abstract:||The depletion of emamectin B 1a in the edible tissues of rainbow trout (Oncorhynchus mykiss) was studied at two temperatures following treatment with emamectin benzoate (Slice®) in feed. Fish approaching market size (400–1500g) were held in tanks supplied with temperature-controlled seawater at 6±1°C (cold water) or 15±1°C (warm water). In each study the medicated group was offered feed containing emamectin benzoate at a nominal dose rate of 50μgkg−1 fish day−1 for 7 days and the control group was offered unmedicated feed. Actual dose rates, calculated from growth rate and feed consumption data, and measured emamectin benzoate concentrations in feed, were 88.6% nominal in the cold water study (96.6% adjusted for feed assay recovery) and 96.8% nominal in the warm water study (105.1% adjusted for feed assay recovery). Concentrations of emamectin B1a were determined in fillet samples collected at intervals from 6h to 77 days post-treatment in the cold water study and 6h to 49 days post-treatment in the warm water study. In the cold water study, mean emamectin B1a residues ranged from 81.8±44.5ngg−1 at 1day post-treatment (102.3±55.7ngg−1 adjusted for recovery) to 13.7±10.5ngg−1 at 77 days post-treatment (17.2±13.1ngg−1). In the warm water study, mean residue concentrations ranged from 64.5±50.3ngg−1 at 6h post-treatment (80.7±62.9ngg−1 adjusted for recovery) to 1.6±1.6ngg−1 at 49 days post-treatment (2.0±2.0ngg−1). In the cold water study, residues in skin and muscle were also determined separately. On average, emamectin B1a concentrations in skin were approximately 1.8 times higher than in muscle. Measured residue levels ranged widely and no detectable residues were found in at least a few individual fish at all time points. This high variability was considered to be due to differences in medicated feed consumption within the experimental population. Depletion of emamectin was faster at 15°C than at 6°C. In both studies the depletion curve showed a small secondary peak at around 90 degree-days. This observation is consistent with recirculation of the compound from a body store.|
|Rights:||The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study.|
ABC Laboratories (Europe) Ltd
Schering-Plough Research Institute
|Roy et al_Aquaculture_2006.pdf||182.63 kB||Adobe PDF||Under Embargo until 31/12/2999 Request a copy|
Note: If any of the files in this item are currently embargoed, you can request a copy directly from the author by clicking the padlock icon above. However, this facility is dependant on the depositor still being contactable at their original email address.
This item is protected by original copyright
Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.
If you believe that any material held in STORRE infringes copyright, please contact email@example.com providing details and we will remove the Work from public display in STORRE and investigate your claim.