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Appears in Collections:Psychology Journal Articles
Peer Review Status: Refereed
Title: Lexical and semantic fluency discrepancy scores in aMCI and early Alzheimer's Disease
Authors: Lonie, Jane A
Herrmann, Lucie L
Tierney, Kevin M
Donaghey, Claire
O'Carroll, Ronan
Lee, Andrew
Ebmeier, Klaus P
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Issue Date: Mar-2009
Publisher: British Psychological Society
Citation: Lonie JA, Herrmann LL, Tierney KM, Donaghey C, O'Carroll R, Lee A & Ebmeier KP (2009) Lexical and semantic fluency discrepancy scores in aMCI and early Alzheimer's Disease, Journal of Neuropsychology, 3 (1), pp. 79-92.
Abstract: Episodic memory is compromised in amnestic mild cognitive impairment (aMCI), but lesser deficits in other cognitive domains are also commonly observed and may be helpful in identifying this group. The relative difference in performance on lexical and semantic fluency tasks may be a sensitive and specific measure in aMCI and early Alzheimer's disease (AD). We compared four groups of participants, 35 early AD, 47 aMCI, 24 healthy controls, and 18 depressive out-patient controls, on semantic and lexical fluency as well as other neuropsychological tests. Early AD and aMCI patients showed a distinct pattern of semantic impairment in the two fluency measures compared with the healthy and depressive controls. The findings implicate early failure of the semantic memory system in aMCI and AD and suggest that consideration of the discrepancy in performance on semantic and lexical fluency measures may help in the early identification of AD.
Type: Journal Article
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Rights: The publisher does not allow this work to be made publicly available in this Repository. Please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author; you can only request a copy if you wish to use this work for your own research or private study.
Notes: 10.1348/174866408X289935
Affiliation: University of Edinburgh
University of Edinburgh
University of Edinburgh
Royal Edinburgh Hospital
Royal Edinburgh Hospital
University of Edinburgh

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