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Appears in Collections:Psychology Journal Articles
Peer Review Status: Refereed
Title: Improving Adherence to Medication in Stroke Survivors (IAMSS): a randomised controlled trial: study protocol
Authors: O'Carroll, Ronan
Martin, Dennis
Johnston, Marie
Sudlow, Cathie
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Issue Date: 2010
Publisher: BioMed Central Ltd.
Citation: O'Carroll R, Martin D, Johnston M & Sudlow C (2010) Improving Adherence to Medication in Stroke Survivors (IAMSS): a randomised controlled trial: study protocol, BMC Neurology, 10.
Abstract: Background: Adherence to therapies is a primary determinant of treatment success, yet the World Health Organisation estimate that only 50% of patients who suffer from chronic diseases adhere to treatment recommendations. In a previous project, we found that 30% of stroke patients reported sub-optimal medication adherence, and this was associated with younger age, greater cognitive impairment, lower perceptions of medication benefits and higher specific concerns about medication. We now wish to pilot a brief intervention aimed at (a) helping patients establish a better medication-taking routine, and (b) eliciting and modifying any erroneous beliefs regarding their medication and their stroke. Methods/Design: Thirty patients will be allocated to a brief intervention (2 sessions) and 30 to treatment as usual. The primary outcome will be adherence measured over 3 months using Medication Event Monitoring System (MEMS) pill containers which electronically record openings. Secondary outcomes will include self reported adherence and blood pressure. Discussion: This study shall also assess uptake/attrition, feasibility, ease of understanding and acceptability of this complex intervention. Trial Registration: Current Controlled Trials ISRCTN38274953
Type: Journal Article
DOI Link:
Rights: Published in BMC Neurology by BioMed Central Ltd.; © 2010 O'Carroll et al; licensee BioMed Central Ltd. Publisher statement: "This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited."
Notes: doi:10.1186/1471-2377-10-15
Affiliation: Psychology
Western General Hospital
University of Aberdeen
Western General Hospital

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