Please use this identifier to cite or link to this item: http://hdl.handle.net/1893/22163
Appears in Collections:Psychology Journal Articles
Peer Review Status: Refereed
Title: Identifying the determinants of adjuvant hormonal therapy medication taking behaviour in women with stages I-III breast cancer: A systematic review and meta-analysis
Authors: Cahir, Caitriona
Guinan, Emer
Dombrowski, Stephan U
Sharp, Linda
Bennett, Kathleen
Contact Email: s.u.dombrowski@stir.ac.uk
Keywords: Breast cancer
Hormonal therapy
Medication taking behaviour
Theoretical Domains
Framework
Adherence
Persistence
Issue Date: Dec-2015
Publisher: Elsevier
Citation: Cahir C, Guinan E, Dombrowski SU, Sharp L & Bennett K (2015) Identifying the determinants of adjuvant hormonal therapy medication taking behaviour in women with stages I-III breast cancer: A systematic review and meta-analysis, Patient Education and Counseling, 98 (12), pp. 1524-1539.
Abstract: Objective: This systematic review and meta-analysis aimed to identify the modifiable determinants of adjuvant hormonal therapy medication taking behaviour (MTB) in women with stage I-III breast cancer in clinical practice settings. Methods: We searched PubMed EMBASE, PsycINFO and CINAHL for articles investigating determinants of adjuvant hormonal therapy. Potentially modifiable determinants were identified and mapped to the 14 domains of the Theoretical Domains Framework (TDF), an integrative framework of theories of behavioural change. Meta-analysis was used to calculate pooled odds ratios for selected determinants. Results: Potentially modifiable determinants were identified in 42 studies and mapped to 9 TDF domains. In meta-analysis treatment side-effects (Domain: Beliefs about Capabilities) and follow-up care with a general practitioner (vs. oncologist) (Social Influences) were significantly negatively associated with persistence (p<0.001) and number of medications (Behaviour Regulation) was significantly positively associated with persistence (p<0.003). Studies did not examine several domains (including Beliefs about Consequences, Intentions, Goals, Social Identity, Emotion and Knowledge) which have been reported to influence MTB in other disease groups. Conclusions: There is some evidence that the domains Beliefs about Capabilities, Behaviour Regulation and Social Influences influence hormonal therapy MTB. Practice implications: Further research is needed to develop effective interventions to improve hormonal therapy MTB.
Type: Journal Article
URI: http://hdl.handle.net/1893/22163
DOI Link: http://dx.doi.org/10.1016/j.pec.2015.05.013
Rights: This item has been embargoed for a period. During the embargo please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study. Accepted refereed manuscript of: Cahir C, Guinan E, Dombrowski SU, Sharp L & Bennett K (2015) Identifying the determinants of adjuvant hormonal therapy medication taking behaviour in women with stages IIII breast cancer: A systematic review and metaanalysis, Patient Education and Counseling, 98 (12), pp. 1524-1539. DOI: 10.1016/j.pec.2015.05.013 © 2015, Elsevier. Licensed under the Creative Commons Attribution- NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/
Affiliation: Trinity College, Dublin
Trinity College, Dublin
Psychology
National Cancer Registry Ireland
Trinity College, Dublin

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