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Appears in Collections:Biological and Environmental Sciences Journal Articles
Peer Review Status: Refereed
Title: Effects of juvenile host density and food availability on adult immune response, parasite resistance and virulence in a Daphnia-parasite system
Authors: Schoebel, Corine N
Auld, Stuart
Spaak, Piet
Little, Tom J
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Issue Date: Apr-2014
Publisher: Public Library of Science
Citation: Schoebel CN, Auld S, Spaak P & Little TJ (2014) Effects of juvenile host density and food availability on adult immune response, parasite resistance and virulence in a Daphnia-parasite system, PLoS ONE, 9 (4), Art. No.: e94569.
Abstract: Host density can increase infection rates and reduce host fitness as increasing population density enhances the risk of becoming infected either through increased encounter rate or because host condition may decline. Conceivably, potential hosts could take high host density as a cue to up-regulate their defence systems. However, as host density usually covaries with food availability, it is difficult to examine the importance of host density in isolation. Thus, we performed two full-factorial experiments that varied juvenile densities of Daphnia magna (a freshwater crustacean) and food availability independently. We also included a simulated high-density treatment, where juvenile experimental animals were kept in filtered media that previously maintained Daphnia at high-density. Upon reaching adulthood, we exposed the Daphnia to their sterilizing bacterial parasite, Pasteuria ramosa, and examined how the juvenile treatments influenced the likelihood and severity of infection (Experiment I) and host immune investment (Experiment II). Neither juvenile density nor food treatments affected the likelihood of infection; however, well-fed hosts that were well-fed as juveniles produced more offspring prior to sterilization than their less well-fed counterparts. By contrast, parasite growth was independent of host juvenile resources or host density. Parasite-exposed hosts had a greater number of circulating haemocytes than controls (i.e., there was a cellular immune response), but the magnitude of immune response was not mediated by food availability or host density. These results suggest that density dependent effects on disease arise primarily through correlated changes in food availability: low food could limit parasitism and potentially curtail epidemics by reducing both the host's and parasite's reproduction as both depend on the same food.
Type: Journal Article
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Rights: © 2014 Schoebel et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Affiliation: Swiss Federal Institute for Forest, Snow and Landscape Research
Biological and Environmental Sciences
ETH Zurich
University of Edinburgh

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