Please use this identifier to cite or link to this item:
Appears in Collections:Biological and Environmental Sciences Journal Articles
Peer Review Status: Refereed
Title: Subclinical infection and asymptomatic carriage of gastrointestinal zoonoses: Occupational exposure, environmental pathways, and the anonymous spread of disease
Authors: Quilliam, Richard
Cross, Paul
Williams, A Prysor
Edwards-Jones, Gareth
Salmon, Roland L
Rigby, Dan
Chalmers, R M
Thomas, D Rh
Jones, David L
Contact Email:
Keywords: Acquired immunity
community epidemiology
disease management
environmental medicine
public health
Issue Date: Oct-2013
Publisher: Cambridge University Press
Citation: Quilliam R, Cross P, Williams AP, Edwards-Jones G, Salmon RL, Rigby D, Chalmers RM, Thomas DR & Jones DL (2013) Subclinical infection and asymptomatic carriage of gastrointestinal zoonoses: Occupational exposure, environmental pathways, and the anonymous spread of disease, Epidemiology and Infection, 141 (10), pp. 2011-2021.
Abstract: Asymptomatic carriage of gastrointestinal zoonoses is more common in people whose profession involves them working directly with domesticated animals. Subclinical infections (defined as an infection in which symptoms are either asymptomatic or sufficiently mild to escape diagnosis) are important within a community as unknowing (asymptomatic) carriers of pathogens do not change their behaviour to prevent the spread of disease; therefore the public health significance of asymptomatic human excretion of zoonoses should not be underestimated. However, optimal strategies for managing diseases where asymptomatic carriage instigates further infection remain unresolved, and the impact on disease management is unclear. In this review we consider the environmental pathways associated with prolonged antigenic exposure and critically assess the significance of asymptomatic carriage in disease outbreaks Although screening high-risk groups for occupationally acquired diseases would be logistically problematical, there may be an economic case for identifying and treating asymptomatic carriage if the costs of screening and treatment are less than the costs of identifying and treating those individuals infected by asymptomatic hosts.
Type: Journal Article
DOI Link:
Rights: This item has been embargoed for a period. During the embargo please use the Request a Copy feature at the foot of the Repository record to request a copy directly from the author. You can only request a copy if you wish to use this work for your own research or private study. Publisher policy allows this work to be made available in this repository. Published in Epidemiology and Infection / Volume 141 / Issue 10 / October 2013, pp 2011-2021 Copyright © Cambridge University Press 2013. The original publication is available at:
Affiliation: Biological and Environmental Sciences
Bangor University
Bangor University
Bangor University
NHS Wales
University of Manchester
Singleton Hospital
NHS Wales
Bangor University

Files in This Item:
File Description SizeFormat 
Epidemiol Infect 2013.pdf140.55 kBAdobe PDFView/Open

This item is protected by original copyright

Items in the Repository are protected by copyright, with all rights reserved, unless otherwise indicated.

If you believe that any material held in STORRE infringes copyright, please contact providing details and we will remove the Work from public display in STORRE and investigate your claim.